Evidence map›Paper›PMID 28567370›Full record

ArticleCanadian journal of gastroenterology & hepatology2017

Maintenance of Remission with Partial Enteral Nutrition Therapy in Pediatric Crohn's Disease: A Retrospective Study.

Jacqueline M Schulman, Liat Pritzker, Ron Shaoul

Abstract readEvaluation Study
In one paragraph

Article in Canadian journal of gastroenterology & hepatology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  3. Prospective study of an adalimumab combined with partial enteral nutrition in the induction period of Crohn's disease.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2024
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  12. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jacqueline M SchulmanThe Ruth and Bruce Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, 3525433 Haifa, Israel.
Liat PritzkerPediatric Gastroenterology & Nutrition Unit, Ruth Children's Hospital, Rambam Medical Center, 3109601 Haifa, Israel.
Ron ShaoulPediatric Gastroenterology & Nutrition Unit, Ruth Children's Hospital, Rambam Medical Center, 3109601 Haifa, Israel.ORCID 0000-0001-5667-8759

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPartial enteral nutrition (PEN) may be helpful for the maintenance of remission in pediatric Crohn's disease patients.

aimsTo evaluate the efficacy of PEN treatment for preventing clinical relapse.

methodsWe retrospectively assessed 42 pediatric Crohn's disease patients who entered clinical remission on 4-12 weeks of exclusive enteral nutrition (EEN) and were maintained on PEN as a supplementary diet. We evaluated the efficacy of the treatment at different time points using the weighted Pediatric Crohn Disease Activity Index (wPCDAI), Physician Global Assessment, laboratory parameters, and growth of each patient. Additionally, we assessed the use of concomitant medications.

resultsThe median length of remission with PEN was 6 (0-36) months. Patients' remission was maintained on PEN without concomitant medications for a median time of zero months (0-16). The mean body mass index in the PEN group increased from 18.1 to 18.8 after six months of PEN. The median wPCDAI decreased from 30 at diagnosis to 5.0 after EEN and increased to 7.5 after three months of PEN. Overall, the median wPCDAI decreased by 26.2.

conclusionsPEN treatment was partially effective in maintaining remission and was able to increase BMI and lower wPCDAI. Most patients required concomitant medication after PEN initiation.

Indexed as

AdolescentChildChild, PreschoolCrohn DiseaseEnteral NutritionFemaleHumansInfantMaleRemission InductionRetrospective StudiesSecondary PreventionTreatment OutcomeYoung Adult

Identifiers

PMID28567370
PMCPMC5439067

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.