Evidence map›Paper›PMID 28567235›Full record

ArticleClinics and practice2017

Investigating Idiopathic Inflammatory Myopathy; Initial Cross Speciality Experience with Use of the Extended Myositis Antibody Panel.

Antoinette O'Connor, Jennifer Mulhall, Sinead M J Harney, John G Ryan, Grainne Murphy, Michael T Henry, Peter Annis, Vincent Tormey, Aisling M Ryan

Abstract read
In one paragraph

Article in Clinics and practice, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Antoinette O'ConnorDepartment of Neurology, Cork University Hospital, Cork, Ireland.
Jennifer MulhallDepartment of Neurology, Cork University Hospital, Cork, Ireland.
Sinead M J HarneyDepartment of Rheumatology, Cork University Hospital, Cork, Ireland.
John G RyanDepartment of Rheumatology, Cork University Hospital, Cork, Ireland.
Grainne MurphyDepartment of Rheumatology, Cork University Hospital, Cork, Ireland.
Michael T HenryDepartment of Respiratory Medicine, Cork University Hospital, Cork, Ireland.
Peter AnnisDepartment of Immunology, Cork University Hospital, Cork, Ireland.
Vincent TormeyDepartment of Immunology, University Hospital, Galway, Ireland.
Aisling M RyanDepartment of Neurology, Cork University Hospital, Cork, Ireland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The discovery of unique autoantibodies has informed and altered our approach to the diagnosis and management of the inflammatory myopathies. This study reports the initial clinical experience of use of the Extended Myositis Antibody (EMA) panel in the largest university teaching hospital in Ireland. We conducted a retrospective review of all patients who had serum samples tested for myositis specific antibodies and myositis associated antibodies from April 2014 to March 2015. A positive EMA panel was of significant clinical utility in facilitating decisions on appropriate investigations, and need for onward referral to other physicians. Furthermore, this paper highlights the diversity of possible presentations of idiopathic inflammatory myopathy with subsequent need for multi-speciality involvement, and serves to heighten awareness among clinicians of the diagnostic use of extended myositis antibody testing in these cases.

Indexed as

Idiopathic inflammatory myopathymyositis-associated autoantibodiesmyositis specific autoantibodies

Identifiers

PMID28567235
PMCPMC5432941

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.