ReviewInternational journal of preventive medicine2017
Penile Inflammatory Skin Disorders and the Preventive Role of Circumcision.
Review in International journal of preventive medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 60 citations in OpenAlex.
- Impact of Sexual Activity on the Risk of Male Genital Tumors: A Systematic Review of the Literature.International journal of environmental research and public health · 2021Pooled it
- Critical evaluation of arguments opposing male circumcision: A systematic review.Journal of evidence-based medicine · 2019Pooled it
- Does the evidence support circumcision of infant males in the United Kingdom?-a systematic review.Translational andrology and urology · 2026Review
- Sex-specific risk factors for genital infections associated with SGLT2 inhibitors in type 2 diabetes: a retrospective cohort study and disproportionality analysis using JADER.Therapeutic advances in drug safety · 2026Article
- Dermoscopic Features of Non-Infectious Balanoposthitis.Journal of clinical medicine · 2025Article
- Advances in the study of the correlation between balanoposthitis and skin microecology.Frontiers in microbiology · 2025Review
- Comparing Penile Problems in Circumcised vs. Uncircumcised Boys: Insights From a Large Commercial Claims Database With a Focus on Provider Type Performing Circumcision.Journal of pediatric surgery · 2024Article
- Neonatal Male Circumcision: Clearly Beneficial for Public Health or an Ethical Dilemma? A Systematic Review.Cureus · 2024Review
- Reply to letter: Erosive balanitis caused by Staphylococcus haemolyticus in a healthy, circumcised adult male.Access microbiology · 2024Article
- What is the medical evidence on non-therapeutic child circumcision?International journal of impotence research · 2023Review
- Evidence-based circumcision policy for Australia.Journal of men's health · 2022Article
- Decline in Frequency of Newborn Male Circumcision After Change in Medicaid Coverage Status in Selected States in the United States.Public health reports (Washington, D.C. : 1974) · 2021Article
- Circumcision in childhood and male sexual function: a blessing or a curse?International journal of impotence research · 2021Review
- Progress on Management of Penile Cancer in 2020.Current treatment options in oncology · 2020Review
- Observational
- Recent advances in understanding and managing Lichen Sclerosus.F1000Research · 2020Review
- Single-Center Analysis of Human Papillomavirus Infection and P16INK4A Expression among Korean Patients with Penile Cancer.BioMed research international · 2019Article
- Increased Risk of Penile Cancer among Men Working in AgricultureAsian Pacific journal of cancer prevention : APJCP · 2018Article
- CDC's Male Circumcision Recommendations Represent a Key Public Health Measure.Global health, science and practice · 2017Article
- Early infant male circumcision: Systematic review, risk-benefit analysis, and progress in policy.World journal of clinical pediatrics · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Penile inflammatory skin conditions such as balanitis and posthitis are common, especially in uncircumcised males, and feature prominently in medical consultations. We conducted a systematic review of the medical literature on PubMed, EMBASE, and Cohrane databases using keywords "balanitis," "posthitis," "balanoposthitis," "lichen sclerosus," "penile inflammation," and "inflammation penis," along with "circumcision," "circumcised," and "uncircumcised." Balanitis is the most common inflammatory disease of the penis. The accumulation of yeasts and other microorganisms under the foreskin contributes to inflammation of the surrounding penile tissue. The clinical presentation of inflammatory penile conditions includes itching, tenderness, and pain. Penile inflammation is responsible for significant morbidity, including acquired phimosis, balanoposthitis, and lichen sclerosus. Medical treatment can be challenging and a cost burden to the health system. Reducing prevalence is therefore important. While topical antifungal creams can be used, usually accompanied by advice on hygiene, the definitive treatment is circumcision. Data from meta-analyses showed that circumcised males have a 68% lower prevalence of balanitis than uncircumcised males and that balanitis is accompanied by a 3.8-fold increase in risk of penile cancer. Because of the high prevalence and morbidity of penile inflammation, especially in immunocompromised and diabetic patients, circumcision should be more widely adopted globally and is best performed early in infancy.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.