Evidence map›Paper›PMID 28567105›Full record

ArticleUltrasound (Leeds, England)2017

Cerebral haemodynamics in early puerperium: A prospective study.

G P Anzola, R Brighenti, M Cobelli, A Giossi, S Mazzucco, S Olivato, E Pari, M P Piras, A Padovani, F Rinaldi and 1 more

Abstract read
In one paragraph

Article in Ultrasound (Leeds, England), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Trial
  2. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

G P AnzolaConsultant Neurologist, Villa Gemma Hospital, Gardone Riviera, Italy.
R BrighentiDepartment of Obstetrics and Gynaecology, Poliambulanza Hospital, Brescia, Italy.
M CobelliDepartment of Radiology, Poliambulanza Hospital, Brescia, Italy.
A GiossiDepartment of Neurology, Azienda Socio Sanitaria Territoriale, Cremona, Italy.
S MazzuccoNuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK.
S OlivatoULSS 22, Verona, Italy.
E PariDeparment of Neurology, Spedali Civili, University of Brescia, Brescia, Italy.
M P PirasDeparment of Neurology, Poliambulanza Hospital, Brescia, Italy.
A PadovaniDeparment of Neurology, Spedali Civili, University of Brescia, Brescia, Italy.
F RinaldiDeparment of Neurology, Spedali Civili, University of Brescia, Brescia, Italy.
G TurriDepartment of Neurosciences, Biomedicine and Movement Sciences, University Hospital of Verona, Verona, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimProspective study on 900 consecutive puerperae to assess normal values and range of the blood flow velocity in the middle cerebral artery in both hemispheres. MATERIAL AND

methodM1 and M2 segments of both middle cerebral arteries were assessed in all subjects within 96 hours of delivery. Mean flow velocity was recorded after adjusting for insonation angle. Lindegaard index (LI = middle cerebral artery-Internal Carotid Artery mean flow velocity ratio) was calculated whenever the mean flow velocity exceeded 100 cm/second. Asymmetry indexes were calculated inter hemispherically for M1 and M2 segments separately.

resultsMean flow velocities were 74 ± 17 and 72 ± 17 in right and 73 ± 17 and 72 ± 17 cm/second in the left M1 and M2, respectively. A total of 136 subjects (12.1%) exceeded the threshold of 100 cm/second, but LI was consistently <3 in all of them. Mean flow velocity was inversely and independently correlated to haemoglobin levels and to parity. Mean asymmetry indexes were 0.25 ± 23 in M1 and 0.45 ± 25 in M2.

conclusionMean flow velocity in the middle cerebral artery of healthy subjects in early puerperium is higher than in age-matched non-puerperal women and may exceed the threshold of 100 cm/second with no evidence of intracranial spasm, because of blood loss during delivery. Mean flow velocity is independently correlated with parity. Right-to-left mean flow velocity asymmetry may reach 50% as a consequence of a transient imbalance in vascular tone regulation.

Indexed as

asymmetry indexMean flow velocitymiddle cerebral arterypuerperium

Identifiers

PMID28567105
PMCPMC5438056

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.