Evidence map›Paper›PMID 28567041›Full record

ArticleFrontiers in immunology2017

Pathogen-Reactive T Helper Cell Analysis in the Pig.

Friederike Ebner, Patrycja Schwiertz, Svenja Steinfelder, Robert Pieper, Jürgen Zentek, Nicole Schütze, Christoph G Baums, Gottfried Alber, Peter Geldhof, Susanne Hartmann

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
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  5. Article
  6. A review of CD4Veterinary immunology and immunopathology · 2024
    Review
  7. Frontiers in immunology · 2024
    Article
  8. Article
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  11. Article
  12. Review
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  14. Frontiers in immunology · 2022
    Article
  15. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Friederike EbnerDepartment of Veterinary Medicine, Institute of Immunology, Freie Universität Berlin, Berlin, Germany.
Patrycja SchwiertzDepartment of Veterinary Medicine, Institute of Immunology, Freie Universität Berlin, Berlin, Germany.
Svenja SteinfelderDepartment of Veterinary Medicine, Institute of Immunology, Freie Universität Berlin, Berlin, Germany.
Robert PieperDepartment of Veterinary Medicine, Institute of Animal Nutrition, Freie Universität Berlin, Berlin, Germany.
Jürgen ZentekDepartment of Veterinary Medicine, Institute of Animal Nutrition, Freie Universität Berlin, Berlin, Germany.
Nicole SchützeFaculty of Veterinary Medicine, Institute of Immunology, Centre for Infectious Diseases, University of Leipzig, Leipzig, Germany.
Christoph G BaumsFaculty of Veterinary Medicine, Institute for Bacteriology and Mycology, Centre for Infectious Diseases, University of Leipzig, Leipzig, Germany.
Gottfried AlberFaculty of Veterinary Medicine, Institute of Immunology, Centre for Infectious Diseases, University of Leipzig, Leipzig, Germany.
Peter GeldhofLaboratory of Parasitology, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium.
Susanne HartmannDepartment of Veterinary Medicine, Institute of Immunology, Freie Universität Berlin, Berlin, Germany.
Freie Universität Berlin · DELeipzig University · DEGhent University · BEUniversity Hospital Leipzig · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is growing interest in studying host-pathogen interactions in human-relevant large animal models such as the pig. Despite the progress in developing immunological reagents for porcine T cell research, there is an urgent need to directly assess pathogen-specific T cells-an extremely rare population of cells, but of upmost importance in orchestrating the host immune response to a given pathogen. Here, we established that the activation marker CD154 (CD40L), known from human and mouse studies, identifies also porcine antigen-reactive CD4

Indexed as

antigen-specificAscaris suumCandida albicansCD154CD40 ligandpigporcine CD4 T cellStreptococcus suis

Identifiers

PMID28567041
PMCPMC5434156
OpenAlexW2616677910

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.