Evidence map›Paper›PMID 28567019›Full record

ArticleFrontiers in physiology2017

Down-Regulation of Cough during Exercise Is Less Frequent in Healthy Children than Adults. Role of the Development and/or Atopy?

Silvia Demoulin-Alexikova, François Marchal, Claude Bonabel, Bruno Demoulin, Laurent Foucaud, Laurianne Coutier-Marie, Cyril E Schweitzer, Iulia Ioan

Open access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Silvia Demoulin-AlexikovaEA 3450 DevAH - Laboratoire de Physiologie, Faculty of Medicine, University of LorraineVandœuvre-lès-Nancy, France.
François MarchalEA 3450 DevAH - Laboratoire de Physiologie, Faculty of Medicine, University of LorraineVandœuvre-lès-Nancy, France.
Claude BonabelService d'Explorations Fonctionnelles Pédiatriques, Hôpital d'enfants de Brabois - CHRU de NancyVandoeuvre-lès-Nancy, France.
Bruno DemoulinEA 3450 DevAH - Laboratoire de Physiologie, Faculty of Medicine, University of LorraineVandœuvre-lès-Nancy, France.
Laurent FoucaudEA 3450 DevAH - Laboratoire de Physiologie, Faculty of Medicine, University of LorraineVandœuvre-lès-Nancy, France.
Laurianne Coutier-MarieEA 3450 DevAH - Laboratoire de Physiologie, Faculty of Medicine, University of LorraineVandœuvre-lès-Nancy, France.
Cyril E SchweitzerEA 3450 DevAH - Laboratoire de Physiologie, Faculty of Medicine, University of LorraineVandœuvre-lès-Nancy, France.
Iulia IoanEA 3450 DevAH - Laboratoire de Physiologie, Faculty of Medicine, University of LorraineVandœuvre-lès-Nancy, France.
Centre Hospitalier Régional et Universitaire de Nancy · FRLaboratoire de Chimie Physique et Microbiologie pour l'Environnement · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cough is typically associated with physical activity in children with asthma, but the characteristics of the relationship between cough and exercise has not been established under physiological conditions. The aim of the study was to describe the effect of exercise on the reflex cough response elicited by a single breath of capsaicin in non-asthmatic children. A group of non-asthmatic adults was studied as reference. Thirty children and 29 adults were recruited. The cough reflex sensitivity to capsaicin was first determined to establish the dose that provokes 5 cough efforts (C5). The number of coughs elicited by C5 (NC5) was then compared at baseline and during a standardized submaximal treadmill exercise. Data are expressed as median (interquartile range). Children and adults showed a significant decrease in NC5 (respectively from 5.0 (4.0-6.0) to 2.5 (2.0-4.0),

Indexed as

adultchildrencoughdevelopmentdown-regulationexercisematuration

Identifiers

PMID28567019
PMCPMC5434114
OpenAlexW2614677999

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.