Evidence map›Paper›PMID 28566946›Full record

ReviewDialogues in clinical neuroscience2017

A multispecies approach for understanding neuroimmune mechanisms of stress.

Terrence Deak, Anastacia Kudinova, Dennis F Lovelock, Brandon E Gibb, Michael B Hennessy

Open access · diamondAbstract readReview
In one paragraph

Review in Dialogues in clinical neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 33 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Psychoneuroimmunology of Meditation.Annals of neurosciences · 2022
    Review
  5. Enhanced Fear Memories and Altered Brain Glucose Metabolism (International journal of molecular sciences · 2022
    Article
  6. Article
  7. Does inflammation link stress to poor COVID-19 outcome?Stress and health : journal of the International Society for the Investigation of Stress · 2021
    Review
  8. Effects of Ketamine on Rodent Fear Memory.International journal of molecular sciences · 2020
    Review
  9. Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Terrence DeakCenter for Affective Science and Department of Psychology, Binghamton University-State University of New York (SUNY), Binghamton, New York, USA.
Anastacia KudinovaCenter for Affective Science and Department of Psychology, Binghamton University-State University of New York (SUNY), Binghamton, New York, USA.
Dennis F LovelockCenter for Affective Science and Department of Psychology, Binghamton University-State University of New York (SUNY), Binghamton, New York, USA.
Brandon E GibbCenter for Affective Science and Department of Psychology, Binghamton University-State University of New York (SUNY), Binghamton, New York, USA.
Michael B HennessyDepartment of Psychology, Wright State University, Dayton, Ohio, USA.
Binghamton University · US

Funding

Social Anxiety, Stress and Ethanol Sensitivity in Adolescence and AdulthoodP50AA017823 · NIAAA · UPSTATE MEDICAL UNIVERSITY · PI Marvin Rafael Diaz · 2009 to 2026
$30.5M
Supplement to MH098060, “Children’s Attentional Biases: A Key Component of Negative Valence Systems.”R01MH098060 · NIMH · STATE UNIVERSITY OF NY,BINGHAMTON · PI GIBB, BRANDON E · 2012 to 2015
$3.1M
Neuroinflammation and social behavior across the lifespanR01AG043467 · NIA · STATE UNIVERSITY OF NY,BINGHAMTON · PI DEAK, TERRENCE · 2014 to 2018
$2.3M
STRESS-INDUCED SICKNESS SOCIAL SEPARATION: DEPRESSIONR15MH068228 · NIMH · WRIGHT STATE UNIVERSITY · PI HENNESSY, MICHAEL B · 2003 to 2013
$1.0M
NIAAA NIH HHS P50 AA017823NIA NIH HHS R01 AG043467NIMH NIH HHS R01 MH098060NIMH NIH HHS R15 MH068228
6 · The paper itself

Abstract

The relationship between stress challenges and adverse health outcomes, particularly for the development of affective disorders, is now well established. The highly conserved neuroimmune mechanisms through which responses to stressors are transcribed into effects on males and females have recently garnered much attention from researchers and clinicians alike. The use of animal models, from mice to guinea pigs to primates, has greatly increased our understanding of these mechanisms on the molecular, cellular, and behavioral levels, and research in humans has identified particular brain regions and connections of interest, as well as associations between stress-induced inflammation and psychiatric disorders. This review brings together findings from multiple species in order to better understand how the mechanisms of the neuroimmune response to stress contribute to stress-related psychopathologies, such as major depressive disorder, schizophrenia, and bipolar disorder.

Indexed as

AnimalsDisease Models, AnimalHumansInflammationMaternal DeprivationMental DisordersNeuroimmunomodulationSex FactorsSocial IsolationStress, PhysiologicalStress, Psychologicaldepressionguinea piginflammatory mediatormicroglianeuroimmune responsenonhuman primatesicknessstress reactivity

Identifiers

PMID28566946
PMCPMC5442363
OpenAlexW2626709355

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.