Evidence map›Paper›PMID 28566897›Full record

Trial reportWorld journal of gastroenterology2017

Low-FODMAP diet reduces irritable bowel symptoms in patients with inflammatory bowel disease.

Natalia Pedersen, Dorit Vedel Ankersen, Maria Felding, Henrik Wachmann, Zsuzsanna Végh, Line Molzen, Johan Burisch, Jens Rikardt Andersen, Pia Munkholm

Open access · hybridAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in World journal of gastroenterology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 103 papers, 11 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
103citing papers in PubMed, 11 pooled it
12.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

103 citing papers in PubMed, 11 syntheses or guidelines pooled it, 199 citations in OpenAlex.

  1. Pooled it
  2. Effects of a Low FODMAP Diet in Inflammatory Bowel Disease and Patient Experiences: A Mixed Methods Systematic Literature Review and Meta-Analysis.Journal of human nutrition and dietetics : the official journal of the British Dietetic Association · 2025
    Pooled it
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  10. Diet and inflammatory bowel disease: The Asian Working Group guidelines.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2019
    Guideline
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43 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Natalia PedersenNatalia Pedersen, Department of Gastroenterology, Slagelse Hospital, 4200 Slagelse, Denmark.
Dorit Vedel AnkersenNatalia Pedersen, Department of Gastroenterology, Slagelse Hospital, 4200 Slagelse, Denmark.
Maria FeldingNatalia Pedersen, Department of Gastroenterology, Slagelse Hospital, 4200 Slagelse, Denmark.
Henrik WachmannNatalia Pedersen, Department of Gastroenterology, Slagelse Hospital, 4200 Slagelse, Denmark.
Zsuzsanna VéghNatalia Pedersen, Department of Gastroenterology, Slagelse Hospital, 4200 Slagelse, Denmark.
Line MolzenNatalia Pedersen, Department of Gastroenterology, Slagelse Hospital, 4200 Slagelse, Denmark.
Johan BurischNatalia Pedersen, Department of Gastroenterology, Slagelse Hospital, 4200 Slagelse, Denmark.
Jens Rikardt AndersenNatalia Pedersen, Department of Gastroenterology, Slagelse Hospital, 4200 Slagelse, Denmark.
Pia MunkholmNatalia Pedersen, Department of Gastroenterology, Slagelse Hospital, 4200 Slagelse, Denmark.
Slagelse Hospital · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo investigate the effect of a low-FODMAP diet on irritable bowel syndrome (IBS)-like symptoms in patients with inflammatory bowel disease (IBD).

methodsThis was a randomised controlled open-label trial of patients with IBD in remission or with mild-to-moderate disease and coexisting IBS-like symptoms (Rome III) randomly assigned to a Low-FODMAP diet (LFD) or a normal diet (ND) for 6 wk between June 2012 and December 2013. Patients completed the IBS symptom severity system (IBS-SSS) and short IBD quality of life questionnaire (SIBDQ) at weeks 0 and 6. The primary end-point was response rates (at least 50-point reduction) in IBS-SSS at week 6 between groups; secondary end-point was the impact on quality of life.

resultsEighty-nine patients, 67 (75%) women, median age 40, range 20-70 years were randomised: 44 to LFD group and 45 to ND, from which 78 patients completed the study period and were included in the final analysis (37 LFD and 41 ND). There was a significantly larger proportion of responders in the LFD group (

conclusionIn a prospective study, a low-FODMAP diet reduced IBS-like symptoms and increased quality of life in patients with IBD in remission.

Indexed as

DietAdultAgedC-Reactive ProteinDisaccharidesFemaleFermentationHumansInflammatory Bowel DiseasesInternetIrritable Bowel SyndromeMaleMiddle AgedMonosaccharidesOligosaccharidesPatient ComplianceC-Reactive ProteinDisaccharidesMonosaccharidesOligosaccharidesInflammatory bowel diseaseIrritable bowel syndromeLow-FODMAP dietWeb-based management

Identifiers

PMID28566897
PMCPMC5434443
OpenAlexW2612882731

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.