Evidence map›Paper›PMID 28566732›Full record

ArticleScientific reports2017

Peptide Markers for Rapid Detection of KPC Carbapenemase by LC-MS/MS.

Honghui Wang, Steven K Drake, Jung-Ho Youn, Avi Z Rosenberg, Yong Chen, Marjan Gucek, Anthony F Suffredini, John P Dekker

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00077909 (Biomarkers and Protein Mass Expression Profiles in Bronchoalveolar Lavage From Patients With Lung Infiltrates), which is not on this map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.3field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00077909 recruitingnot on this map

Biomarkers and Protein Mass Expression Profiles in Bronchoalveolar Lavage From Patients With Lung Infiltrates

TypeobservationalSponsorNational Institutes of Health Clinical Center (CC)Ran2004Enrolled750ConditionsPneumonia, Pulmonary Disease, Lung Disease
3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 31 citations in OpenAlex.

  1. Review
  2. Review
  3. Proteomic assay for rapid characterisation of Staphylococcus aureus antimicrobial resistance mechanisms directly from blood cultures.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2024
    Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. High-performance method to detection of Klebsiella pneumoniae Carbapenemase in Enterobacterales by LC-MS/MS.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2020
    Article
  13. Direct detection of intactClinical mass spectrometry (Del Mar, Calif.) · 2020
    Article
  14. Review
  15. Rapid Identification of Carbapenemase-producingThe Eurasian journal of medicine · 2019
    Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Honghui WangCritical Care Medicine Department, Clinical Center, National Institutes of Health, Bethesda, Maryland, USA.
Steven K DrakeCritical Care Medicine Department, Clinical Center, National Institutes of Health, Bethesda, Maryland, USA.
Jung-Ho YounMicrobiology Service, Department of Laboratory Medicine, Clinical Center, National Institutes of Health, Bethesda, Maryland, USA.
Avi Z RosenbergKidney Disease Section, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, USA.
Yong ChenProteomics Core Facility, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland, USA.
Marjan GucekProteomics Core Facility, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland, USA.
Anthony F SuffrediniCritical Care Medicine Department, Clinical Center, National Institutes of Health, Bethesda, Maryland, USA.
John P DekkerMicrobiology Service, Department of Laboratory Medicine, Clinical Center, National Institutes of Health, Bethesda, Maryland, USA. john.dekker@nih.gov.
National Institutes of Health Clinical Center · USNational Heart Lung and Blood Institute · USJohns Hopkins University · US

Funding

Proteomics CoreZICHL005903 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI GUCEK, MARJAN · 2009 to 2022
$23.3M
Diagnostic and Prognostic Biomarkers in PneumoniaZIACL008063 · CLC · CLINICAL CENTER · PI SUFFREDINI, ANTHONY F. · 2009 to 2025
$0k
Novel Applications of Mass Spectrometry and Proteomics to Infectious Disease DiagnosticsZIACL080019 · CLC · CLINICAL CENTER · PI DEKKER, JOHN · 2014 to 2018
$0k
6 · The paper itself

Abstract

Carbapenemase producing organisms (CPOs) represent an urgent public health threat, and the need for new rapid methods to detect these organisms has been widely recognized. CPOs carrying the Klebsiella pneumoniae carbapenemase (bla

Indexed as

Bacterial Proteinsbeta-LactamasesCarbapenemsChromatography, LiquidHumansKlebsiella InfectionsKlebsiella pneumoniaeMicrobial Sensitivity TestsPeptidesTandem Mass SpectrometryBacterial Proteinsbeta-LactamasescarbapenemaseCarbapenemsPeptides

Identifiers

PMID28566732
PMCPMC5451396
OpenAlexW2617968425

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.