Evidence map›Paper›PMID 28566601›Full record

ArticleInternal medicine (Tokyo, Japan)2017

Challenging Differential Diagnosis of Hypergastremia and Hyperglucagonemia with Chronic Renal Failure: Report of a Case with Multiple Endocrine Neoplasia Type 1.

Takaaki Murakami, Takeshi Usui, Yuji Nakamoto, Akio Nakajima, Yuki Mochida, Sumio Saito, Takahiro Shibayama, Nobuhisa Yamazaki, Tomonobu Hatoko, Tomoko Kato and 3 more

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PubMed Full text at PMC Publisher
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Takaaki MurakamiDepartment of Diabetes and Endocrinology, Osaka Red Cross Hospital, Japan.
Takeshi UsuiClinical Research Institute, National Hospital Organization Kyoto Medical Center, Japan.
Yuji NakamotoDepartment of Diagnostic Imaging and Nuclear Medicine, Graduate School of Medicine, Kyoto University, Japan.
Akio NakajimaDepartment of Surgery, Osaka Red Cross Hospital, Japan.
Yuki MochidaDepartment of Surgery, Osaka Red Cross Hospital, Japan.
Sumio SaitoDepartment of Gastroenterology and Hepatology, Osaka Red Cross Hospital, Japan.
Takahiro ShibayamaDepartment of Pathology, Osaka Red Cross Hospital, Japan.
Nobuhisa YamazakiDepartment of Respiratory Surgery, Osaka Red Cross Hospital, Japan.
Tomonobu HatokoDepartment of Diabetes and Endocrinology, Osaka Red Cross Hospital, Japan.
Tomoko KatoDepartment of Diabetes and Endocrinology, Osaka Red Cross Hospital, Japan.
Shin YonemitsuDepartment of Diabetes and Endocrinology, Osaka Red Cross Hospital, Japan.
Seiji MuroDepartment of Diabetes and Endocrinology, Osaka Red Cross Hospital, Japan.
Shogo OkiDepartment of Diabetes and Endocrinology, Osaka Red Cross Hospital, Japan.
Osaka Red Cross Hospital · JPKyoto Medical Center · JPKyoto University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 53-year-old woman developed end-stage renal failure during a 15-year clinical course of primary hyperparathyroidism and was referred to our hospital for evaluation of suspected multiple endocrine neoplasia type 1 (MEN1). Genetic testing revealed a novel deletion mutation at codon 467 in exon 10 of the MEN1 gene. Systemic and selective arterial calcium injection (SACI) testing revealed hyperglucagonemia and hypergastrinemia with positive gastrin responses. A pathological examination revealed glucagonoma and a lymph node gastrinoma. The findings in this case indicate the importance of early diagnosis of MEN1 and demonstrate the utility of systemic and SACI testing in renal failure cases.

Indexed as

Diagnosis, DifferentialFemaleGastrinomaGlucagonomaHumansKidney Failure, ChronicLymph NodesMiddle AgedMultiple Endocrine Neoplasia Type 1Pancreatic NeoplasmsProto-Oncogene ProteinsRenal Insufficiency, ChronicMEN1 protein, humanProto-Oncogene ProteinsAIMAHcalcium testgastrinomaglucagonomaMEN1renal failure

Identifiers

PMID28566601
PMCPMC5498202
OpenAlexW2620265398

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.