Evidence map›Paper›PMID 28566502›Full record

ArticleAmerican journal of physiology. Renal physiology2017

Inhibition of HDAC enhances STAT acetylation, blocks NF-κB, and suppresses the renal inflammation and fibrosis in

Prerna Kumar, Venkateswara R Gogulamudi, Ramu Periasamy, Giri Raghavaraju, Umadevi Subramanian, Kailash N Pandey

Open access · bronzeAbstract read
In one paragraph

Article in American journal of physiology. Renal physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 68 papers.

0numbers the graph read from it
0cells of the map it votes in
68citing papers in PubMed
6.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

68 citing papers in PubMed, 90 citations in OpenAlex.

  1. Article
  2. Renal Tubule Cell-SpecificHypertension (Dallas, Tex. : 1979) · 2026
    Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Histone deacetylases and their inhibitors in kidney diseases.Molecular therapy : the journal of the American Society of Gene Therapy · 2025
    Review
  10. Review
  11. Article
  12. Article
  13. Sex-specific modulation of renal epigenetic and injury markers in aging kidney.American journal of physiology. Renal physiology · 2024
    Article
  14. Epigenetic mechanisms differentially regulate blood pressure and renal dysfunction in male and female Npr1 haplotype mice.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2024
    Article
  15. Review
  16. Review
  17. Article
  18. Review
  19. Review
  20. Gut microbial metabolites SCFAs and chronic kidney disease.Journal of translational medicine · 2024
    Review

8 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Prerna KumarDepartment of Physiology, Tulane University Health Sciences Center, School of Medicine, New Orleans, Louisiana.
Venkateswara R GogulamudiDepartment of Physiology, Tulane University Health Sciences Center, School of Medicine, New Orleans, Louisiana.
Ramu PeriasamyDepartment of Physiology, Tulane University Health Sciences Center, School of Medicine, New Orleans, Louisiana.
Giri RaghavarajuDepartment of Physiology, Tulane University Health Sciences Center, School of Medicine, New Orleans, Louisiana.
Umadevi SubramanianDepartment of Physiology, Tulane University Health Sciences Center, School of Medicine, New Orleans, Louisiana.
Kailash N PandeyDepartment of Physiology, Tulane University Health Sciences Center, School of Medicine, New Orleans, Louisiana kpandey@tulane.edu.
Tulane University · US

Funding

The role of the CMV-associated reactive oxygen species in age-relatedP20GM103629 · NIGMS · TULANE UNIVERSITY OF LOUISIANA · PI JAZWINSKI, S MICHAL · 2012 to 2021
$22.4M
Study of ANP Receptor:Gene Targeting and ExpressionR01HL062147 · NHLBI · TULANE UNIVERSITY OF LOUISIANA · PI PANDEY, KAILASH N · 1998 to 2020
$5.0M
NHLBI NIH HHS R01 HL062147NIGMS NIH HHS P20 GM103629
6 · The paper itself

Abstract

Guanylyl cyclase/natriuretic peptide receptor-A (GC-A/NPRA) plays a critical role in the regulation of blood pressure and fluid volume homeostasis. Mice lacking functional

Indexed as

HaplotypesAcetylationAnimalsAnti-Inflammatory AgentsBlood PressureButyric AcidCytokinesDisease Models, AnimalFibrosisGenetic Predisposition to DiseaseHistone Deacetylase 1Histone Deacetylase 2Histone Deacetylase InhibitorsInflammation MediatorsKidneyMaleAnti-Inflammatory Agentsatrial natriuretic factor receptor AButyric AcidCytokinesHdac1 protein, mouseHdac2 protein, mouseHistone Deacetylase 1Histone Deacetylase 2Histone Deacetylase InhibitorsInflammation MediatorsReceptors, Atrial Natriuretic FactorRela protein, mouseStat1 protein, mouseSTAT1 Transcription FactorTranscription Factor RelATretinoinnatriuretic peptide receptor ANpr1 gene disruptionproinflammatory cytokinesrenal fibrosisretinoic acidsodium butyrate

Identifiers

PMID28566502
PMCPMC5625105
OpenAlexW2619267148

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.