Evidence map›Paper›PMID 28566496›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2017

Phosphate is the third nutrient monitored by TOR in

Ning-Ning Liu, Peter R Flanagan, Jumei Zeng, Niketa M Jani, Maria E Cardenas, Gary P Moran, Julia R Köhler

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
4.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 65 citations in OpenAlex.

  1. Article
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  5. Review
  6. A COmBio · 2024
    Article
  7. bioRxiv : the preprint server for biology · 2024
    Article
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  15. Review
  16. Article
  17. The phosphate language of fungi.Trends in microbiology · 2022
    Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Ning-Ning LiuBoston Children's Hospital and Harvard Medical School, Boston, MA 02115.
Peter R FlanaganDivision of Oral Biosciences, School of Dental Science, Trinity College Dublin, Dublin 2, Ireland.
Jumei ZengBoston Children's Hospital and Harvard Medical School, Boston, MA 02115.
Niketa M JaniBoston Children's Hospital and Harvard Medical School, Boston, MA 02115.
Maria E CardenasDepartment of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, NC 27710.
Gary P MoranDivision of Oral Biosciences, School of Dental Science, Trinity College Dublin, Dublin 2, Ireland.
Julia R KöhlerBoston Children's Hospital and Harvard Medical School, Boston, MA 02115; julia.koehler@childrens.harvard.edu.
Boston Children's Hospital · USHarvard University · USTrinity College Dublin · IEDuke Medical Center · US

Funding

The opportunist Candida albicans: yeast proliferation and nutritional signalingR01AI095305 · NIAID · BOSTON CHILDREN'S HOSPITAL · PI KOEHLER, JULIA R · 2013 to 2017
$2.2M
Activation of rapamycin-sensitive TORC1 by endomembrane amino acid transportersR01CA154499 · NCI · DUKE UNIVERSITY · PI CARDENAS-CORONA, MARIA E · 2011 to 2015
$1.6M
New elements of the Target of Rapamycin pathway in Candida albicansR21AI096054 · NIAID · BOSTON CHILDREN'S HOSPITAL · PI KOEHLER, JULIA R · 2011 to 2012
$478k
NCI NIH HHS R01 CA154499NIAID NIH HHS R01 AI095305NIAID NIH HHS R21 AI096054
6 · The paper itself

Abstract

The Target of Rapamycin (TOR) pathway regulates morphogenesis and responses to host cells in the fungal pathogen

Indexed as

Antifungal AgentsCandida albicansFungal ProteinsGene DeletionGenes, FungalHyphaeMechanistic Target of Rapamycin Complex 1Models, BiologicalMonomeric GTP-Binding ProteinsMutationPhosphatesProton-Phosphate SymportersRegulonSaccharomyces cerevisiae ProteinsSignal TransductionAntifungal AgentsFungal ProteinsMechanistic Target of Rapamycin Complex 1Monomeric GTP-Binding ProteinsPHO84 protein, S cerevisiaePhosphatesProton-Phosphate SymportersSaccharomyces cerevisiae Proteinsamphotericin Bantifungaldrug potentiationechinocandinribosomal protein S6 phosphorylation

Identifiers

PMID28566496
PMCPMC5474788
OpenAlexW2952718060

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.