Evidence map›Paper›PMID 28566483›Full record

ReviewProceedings. Biological sciences2017

The sources of adaptive variation.

Deborah Charlesworth, Nicholas H Barton, Brian Charlesworth

Abstract readReview
In one paragraph

Review in Proceedings. Biological sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 78 papers.

0numbers the graph read from it
0cells of the map it votes in
78citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

78 citing papers in PubMed.

  1. Article
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  4. Whole-genome combinatorial gene fusions generate novel genes for advanced microbial trait development.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  5. Article
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  13. Review
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  18. Evolutionary psychiatry: foundations, progress and challenges.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2023
    Article
  19. Article
  20. A generalised approach to the study and understanding of adaptive evolution.Biological reviews of the Cambridge Philosophical Society · 2023
    Article

18 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Deborah CharlesworthInstitute of Evolutionary Biology, School of Biological Sciences, University of Edinburgh, Charlotte Auerbach Road, Edinburgh EH9 3FL, UK.ORCID http://orcid.org/0000-0002-3939-9122
Nicholas H BartonInstitute of Science and Technology Austria, Klosterneuburg 3400, Austria.ORCID http://orcid.org/0000-0002-8548-5240
Brian CharlesworthInstitute of Evolutionary Biology, School of Biological Sciences, University of Edinburgh, Charlotte Auerbach Road, Edinburgh EH9 3FL, UK brian.charlesworth@ed.ac.uk.ORCID http://orcid.org/0000-0002-2706-355X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The role of natural selection in the evolution of adaptive phenotypes has undergone constant probing by evolutionary biologists, employing both theoretical and empirical approaches. As Darwin noted, natural selection can act together with other processes, including random changes in the frequencies of phenotypic differences that are not under strong selection, and changes in the environment, which may reflect evolutionary changes in the organisms themselves. As understanding of genetics developed after 1900, the new genetic discoveries were incorporated into evolutionary biology. The resulting general principles were summarized by Julian Huxley in his 1942 book

Indexed as

Biological EvolutionGenetic VariationSelection, GeneticAdaptation, BiologicalDevelopmental BiologyEnvironmentEpigenesis, Geneticepigenetic inheritanceextended evolutionary synthesismodern synthesismutationnatural selection

Identifiers

PMID28566483
PMCPMC5454256

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.