Evidence map›Paper›PMID 28566436›Full record

ArticleMolecular cancer therapeutics2017

Reactivation of the p90RSK-CDC25C Pathway Leads to Bypass of the Ganetespib-Induced G

Suman Chatterjee, Eric H-B Huang, Ian Christie, Timothy F Burns

Open access · greenAbstract read
In one paragraph

Article in Molecular cancer therapeutics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 17 citations in OpenAlex.

  1. Regulatory role of the miR-142-3p/Translational lung cancer research · 2024
    Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. TargetingInternational journal of molecular sciences · 2020
    Review
  7. Review
  8. Article
  9. Unexpected Activities in Regulating Ciliation Contribute to Off-target Effects of Targeted Drugs.Clinical cancer research : an official journal of the American Association for Cancer Research · 2019
    Article
  10. Targeting Heat Shock Proteins in Cancer: A Promising Therapeutic Approach.International journal of molecular sciences · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Suman ChatterjeeDepartment of Medicine, Division of Hematology Oncology, University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania.
Eric H-B HuangDepartment of Medicine, Division of Hematology Oncology, University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania.
Ian ChristieDepartment of Medicine, Division of Hematology Oncology, University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania.
Timothy F BurnsDepartment of Medicine, Division of Hematology Oncology, University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania. burnstf@upmc.edu.
UPMC Hillman Cancer Center · US

Funding

VECTOR CORE FACILITYP30CA047904 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Jessie Nedrow · 1988 to 2026
$158.0M
Vitamin D3 Modulation of Inflammation and Lung Cancer RiskP50CA090440 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI DACIC, SANJA · 2001 to 2015
$34.6M
LUNGevity Foundation 2013-01NCI NIH HHS P30 CA047904NCI NIH HHS P50 CA090440
6 · The paper itself

Abstract

A subset of non-small cell lung cancers (NSCLC) are dependent upon oncogenic driver mutations, including the most frequently observed driver mutant

Indexed as

Drug Resistance, NeoplasmCarcinoma, Non-Small-Cell Lungcdc25 PhosphatasesCell Cycle CheckpointsCell Line, TumorDocetaxelG2 PhaseHEK293 CellsHumansLung NeoplasmsMitosisMutationProto-Oncogene Proteins p21(ras)Ribosomal Protein S6 Kinases, 90-kDaSignal TransductionTaxoidsCDC25C protein, humancdc25 PhosphatasesDocetaxelKRAS protein, humanProto-Oncogene Proteins p21(ras)Ribosomal Protein S6 Kinases, 90-kDaSTA 9090TaxoidsTriazoles

Identifiers

PMID28566436
PMCPMC5544554
OpenAlexW2618840872

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.