Evidence map›Paper›PMID 28566382›Full record

ArticleJournal of virology2017

Human Papillomavirus Major Capsid Protein L1 Remains Associated with the Incoming Viral Genome throughout the Entry Process.

Stephen DiGiuseppe, Malgorzata Bienkowska-Haba, Lucile G M Guion, Timothy R Keiffer, Martin Sapp

Open access · bronzeAbstract read
In one paragraph

Article in Journal of virology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 66 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Stephen DiGiuseppeDepartment of Microbiology and Immunology, Center for Molecular and Tumor Virology, Feist-Weiller Cancer Center, LSU Health Shreveport, Shreveport, Louisiana, USA sdigiu@lsuhsc.edu msapp1@lsuhsc.edu.
Malgorzata Bienkowska-HabaDepartment of Microbiology and Immunology, Center for Molecular and Tumor Virology, Feist-Weiller Cancer Center, LSU Health Shreveport, Shreveport, Louisiana, USA.
Lucile G M GuionDepartment of Microbiology and Immunology, Center for Molecular and Tumor Virology, Feist-Weiller Cancer Center, LSU Health Shreveport, Shreveport, Louisiana, USA.
Timothy R KeifferCenter for Microbial Pathogenesis, Parker H. Petit Science Center, Georgia State University, Atlanta, Georgia, USA.
Martin SappDepartment of Microbiology and Immunology, Center for Molecular and Tumor Virology, Feist-Weiller Cancer Center, LSU Health Shreveport, Shreveport, Louisiana, USA sdigiu@lsuhsc.edu msapp1@lsuhsc.edu.
Louisiana State University Health Sciences Center Shreveport · USGeorgia State University · US

Funding

COBRE Center for Molecular and Tumor VirologyP30GM110703 · NIGMS · LOUISIANA STATE UNIV HSC SHREVEPORT · PI SAPP, MARTIN · 2014 to 2018
$4.8M
COBRE Center for Molecular and Tumor VirologyP20GM103433 · NIGMS · LOUISIANA STATE UNIV HSC SHREVEPORT · PI O'CALLAGHAN, DENNIS JOHN · 2012 to 2012
$1.9M
Cell surface events of human papillomavirus type 16 and 18 infectionR01AI081809 · NIAID · LOUISIANA STATE UNIV HSC SHREVEPORT · PI SAPP, MARTIN · 2009 to 2013
$1.8M
NIAID NIH HHS R01 AI081809NIGMS NIH HHS P20 GM103433NIGMS NIH HHS P30 GM110703
6 · The paper itself

Abstract

During infectious entry, acidification within the endosome triggers uncoating of the human papillomavirus (HPV) capsid, whereupon host cyclophilins facilitate the release of most of the major capsid protein, L1, from the minor capsid protein L2 and the viral genome. The L2/DNA complex traffics to the

Indexed as

HPV16HPV entryL1 proteinL2 proteinmitosisnuclear transportvirus trafficking

Identifiers

PMID28566382
PMCPMC5533910
OpenAlexW2619962752

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.