Evidence map›Paper›PMID 28566314›Full record

ArticleJournal of clinical microbiology2017

T2 Magnetic Resonance Assay-Based Direct Detection of Three Lyme Disease-Related Borrelia Species in Whole-Blood Samples.

Jessica L Snyder, Heidi Giese, Cheryl Bandoski-Gralinski, Jessica Townsend, Beck E Jacobson, Robert Shivers, Anna M Schotthoefer, Thomas R Fritsche, Clayton Green, Steven M Callister and 2 more

Abstract readEvaluation Study
In one paragraph

Article in Journal of clinical microbiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Detection of Borrelia burgdorferi Cell-free DNA in Human Plasma Samples for Improved Diagnosis of Early Lyme Borreliosis.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2021
    Article
  5. Laboratory Diagnosis of Lyme Borreliosis.Clinical microbiology reviews · 2021
    Review
  6. Direct Diagnostic Tests for Lyme Disease.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2019
    Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Jessica L SnyderT2 Biosystems, Lexington, Massachusetts, USA.ORCID 0000-0001-8179-8998
Heidi GieseT2 Biosystems, Lexington, Massachusetts, USA.
Cheryl Bandoski-GralinskiT2 Biosystems, Lexington, Massachusetts, USA.
Jessica TownsendT2 Biosystems, Lexington, Massachusetts, USA.
Beck E JacobsonT2 Biosystems, Lexington, Massachusetts, USA.
Robert ShiversT2 Biosystems, Lexington, Massachusetts, USA.
Anna M SchotthoeferMarshfield Clinic, Marshfield, Wisconsin, USA.
Thomas R FritscheMarshfield Clinic, Marshfield, Wisconsin, USA.
Clayton GreenMarshfield Clinic, Marshfield, Wisconsin, USA.
Steven M CallisterGundersen Health System, La Crosse, Wisconsin, USA.
John A BrandaMassachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA.
Thomas J LoweryT2 Biosystems, Lexington, Massachusetts, USA tlowery@t2biosystems.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In early Lyme disease (LD), serologic testing is insensitive and seroreactivity may reflect active or past infection. In this study, we evaluated a novel assay for the direct detection of three species of

Indexed as

AdolescentAdultAgedAged, 80 and overBacteriological TechniquesBorreliaHumansLyme DiseaseMagnetic Resonance SpectroscopyMiddle AgedMolecular Diagnostic TechniquesNucleic Acid Amplification TechniquesYoung AdultdiagnosticsLyme disease

Identifiers

PMID28566314
PMCPMC5527424

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.