Evidence map›Paper›PMID 28566292›Full record

Trial reportCirculation. Cardiovascular interventions2017

Effect of Permanent Right Internal Mammary Artery Closure on Coronary Collateral Function and Myocardial Ischemia.

Michael Stoller, Christian Seiler

2 registry-linked trialsOpen access · hybridAbstract readClinical Trial
In one paragraph

Trial report in Circulation. Cardiovascular interventions, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02475408 phase1 / phase2completednot on this map

Effect of Permanent Internal Mammary Artery Occlusion on Extracardiac Coronary Collateral Supply

TypeinterventionalSponsorInsel Gruppe AG, University Hospital BernRan2014 to 2016Enrolled50ConditionsCirculation, Collateral, Coronary Artery Disease, Internal Mammary-Coronary Artery Anastomosis, IschemiaArmsAmplatzer vascular plug
NCT03710070 nacompletednot on this mapstarted 2019, after this paper: background citation

Clinical Efficacy of Permanent Internal Mammary Artery Occlusion in Stable Coronary Artery Disease

TypeinterventionalSponsorInsel Gruppe AG, University Hospital BernRan2019 to 2022Enrolled100ConditionsCoronary Artery Disease, Internal Mammary-Coronary Artery Anastomosis, Ischemia, Circulation, CollateralArmsAmplatzer vascular plug 4, Sham Control
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Cobra Venom Factor Boosts Arteriogenesis in Mice.International journal of molecular sciences · 2022
    Article
  3. Article
  4. Article
  5. Review
  6. Cardioprotection during ischemia by coronary collateral growth.American journal of physiology. Heart and circulatory physiology · 2019
    Review
  7. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Michael StollerFrom the Department of Cardiology, Bern University Hospital, Switzerland.
Christian SeilerFrom the Department of Cardiology, Bern University Hospital, Switzerland. christian.seiler@insel.ch.
University Hospital of Bern · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe objective of this study is to test the effect of permanent right internal mammary artery device closure on coronary collateral function and myocardial ischemia. METHODS AND

resultsThis was a prospective, open-label clinical trial in 50 patients with coronary artery disease. The primary study end point was coronary collateral flow index as obtained during a 1-minute proximal right coronary artery (RCA) and left coronary artery balloon occlusion at baseline before and at follow-up examination 6 weeks after distal right internal mammary artery device closure. Collateral flow index is the ratio between simultaneously recorded mean coronary occlusive pressure divided by mean aortic pressure, both subtracted by central venous pressure. Secondary study end points were fractional flow reserve during vessel patency, the quantitative intracoronary ECG ST-segment elevation, and angina pectoris during the same 1-minute coronary occlusion. Collateral flow index in the untreated RCA and left coronary artery changed from 0.071±0.082 at baseline to 0.132±0.117 (

conclusionsPermanent right internal mammary artery device closure seems to augment extracardiac ipsilateral coronary supply to the effect of reducing ischemia in the dependent myocardial region. CLINICAL

trial registrationURL: http://www.clinicaltrials.gov. Unique identifier: NCT02475408.

Indexed as

Collateral CirculationCoronary CirculationVascular Closure DevicesAgedBlood Flow VelocityCardiac CatheterizationCoronary AngiographyCoronary Artery DiseaseCoronary VesselsElectrocardiographyFeasibility StudiesFemaleFractional Flow Reserve, MyocardialHumansMaleMammary Arteriesarteriogenesiscollateral circulationcoronary circulationinternal mammary arterymyocardial ischemia

Identifiers

PMID28566292
PMCPMC5482561
OpenAlexW2619755482

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.