Evidence map›Paper›PMID 28566286›Full record

ArticleThe Journal of biological chemistry2017

Rab35 protein regulates evoked exocytosis of endothelial Weibel-Palade bodies.

Anja Biesemann, Alexandra Gorontzi, Francis Barr, Volker Gerke

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 39 citations in OpenAlex.

  1. RAB5C Increases Endothelial Release of VWF by Regulating Vesicle Trafficking.Arteriosclerosis, thrombosis, and vascular biology · 2026
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  8. Mucopolysaccharidoses and the blood-brain barrier.Fluids and barriers of the CNS · 2022
    Review
  9. Article
  10. Tip-end fusion of a rod-shaped secretory organelle.Cellular and molecular life sciences : CMLS · 2022
    Article
  11. Spire1 and Myosin Vc promote CaCellular and molecular life sciences : CMLS · 2022
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Anja BiesemannInstitute of Medical Biochemistry, Center for Molecular Biology of Inflammation, University of Münster, D-48149 Münster, Germany.
Alexandra GorontziInstitute of Medical Biochemistry, Center for Molecular Biology of Inflammation, University of Münster, D-48149 Münster, Germany.
Francis BarrDepartment of Biochemistry, University of Oxford, Oxford OX1 3QU, United Kingdom.
Volker GerkeInstitute of Medical Biochemistry, Center for Molecular Biology of Inflammation, University of Münster, D-48149 Münster, Germany. Electronic address: gerke@uni-muenster.de.
University of Münster · DEUniversity of Oxford · GB

Funding

Wellcome Trust
6 · The paper itself

Abstract

Weibel-Palade bodies (WPB) are secretory organelles of endothelial cells that undergo evoked exocytosis following intracellular Ca

Indexed as

ExocytosisADP-Ribosylation Factor 6ADP-Ribosylation FactorsAmino Acid SubstitutionCalcium SignalingCells, CulturedDown-RegulationEndothelium, VascularGreen Fluorescent ProteinsGTPase-Activating ProteinsHistamineHumansHuman Umbilical Vein Endothelial CellsImmunoprecipitationMembrane ProteinsMutagenesis, Site-DirectedACAP2 protein, humanADP-Ribosylation Factor 6ADP-Ribosylation FactorsARF6 protein, humanGreen Fluorescent ProteinsGTPase-Activating ProteinsHistamineMembrane ProteinsRAB35 protein, humanrab GTP-Binding ProteinsRecombinant Fusion ProteinsTBC1D10A protein, humancalciumCalciumendothelial cellendothelial cellsmembrane trafficmembrane traffickingRabvascular biologyvon-Willebrand factor

Identifiers

PMID28566286
PMCPMC5512060
OpenAlexW2617719310

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.