Evidence map›Paper›PMID 28566221›Full record

ReviewGynecologic oncology2017

Sentinel lymph node mapping and staging in endometrial cancer: A Society of Gynecologic Oncology literature review with consensus recommendations.

Robert W Holloway, Nadeem R Abu-Rustum, Floor J Backes, John F Boggess, Walter H Gotlieb, W Jeffrey Lowery, Emma C Rossi, Edward J Tanner, Rebecca J Wolsky

8 registry-linked trialsOpen access · greenAbstract readConsensus StatementReview
In one paragraph

Review in Gynecologic oncology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 8 registered trials, which are not on this map. Cited by 141 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
141citing papers in PubMed, 5 pooled it
34.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03366051 naunknown statusnot on this map

Sentinel Node Mapping Versus Sentinel Node Mapping With Systematic Lymphadenectomy in High Risk Endometrial Cancer: a Open Label, Non-inferiority, Randomized Trial.

TypeinterventionalSponsorAC Camargo Cancer CenterRan2017 to 2024Enrolled178ConditionsEndometrial Cancer, Lymph Node MetastasesArmsSentinel Node Mapping, Lymphadenectomy
NCT03778255 naunknown statusnot on this mapstarted 2018, after this paper: background citation

Comparing the Diagnostic Value of Different Lymph Node Tracing Methods in Detecting Sentinel Lymph Node Metastasis in Endometrial Cancer

TypeinterventionalSponsorPeking University People's HospitalRan2018 to 2020Enrolled635ConditionsEndometrial NeoplasmsArmsSentinel Lymph Node Biopsy
NCT03778268 naunknown statusnot on this mapstarted 2018, after this paper: background citation

Comparing the Diagnostic Value of Different Lymph Node Tracing Methods in Detecting Sentinel Lymph Node Metastasis in Early Cervical Cancer

TypeinterventionalSponsorPeking University People's HospitalRan2018 to 2020Enrolled1,143ConditionsUterine Cervical NeoplasmsArmssentinel lymph node biopsy
NCT04894552 naunknown statusnot on this mapstarted 2020, after this paper: background citation

Complications of Laparoscopic Hysterectomy and Sentinel Lymph Node Biopsy for Endometrial Carcinoma

TypeinterventionalSponsorAin Shams Maternity HospitalRan2020 to 2021Enrolled20ConditionsLaparoscopic Hysterectomy and Sentinel Lymph Node BiopsyArmsLaparoscopic Hysterectomy and Sentinel Lymph Node Biopsy for Endometrial Carcinoma
NCT06163963 naunknown statusnot on this mapstarted 2023, after this paper: background citation

Sentinel Lymph Node Mapping with Double Tracer and Double Injection Sites in Early-Stage Endometrium Cancer

TypeinterventionalSponsorIstanbul UniversityRan2023 to 2026Enrolled100ConditionsSentinel Lymph Node, Endometrial CancerArmsSentinel Lymph Node Mapping With Double Tracer and Double Injection Sites in Early-Stage Endometrium Cancer, charcoal injection to uterus to map sentinel lymph nodes
NCT06694116 naactive not recruitingnot on this mapstarted 2024, after this paper: background citation

Charcoal Carbon Black Dye Use in Sentinel Lymph Node Mapping in Early Stage Vulvar Cancer

TypeinterventionalSponsorIstanbul UniversityRan2024 to 2026Enrolled40ConditionsVulval Cancer, Sentinel Lymph Node DetectionArmssentinel lymph node biopsy using carbon dye
NCT06697054 naactive not recruitingnot on this mapstarted 2024, after this paper: background citation

Use of Charcoal Carbon Dye in Sentinel Lymph Node (SLN) Mapping in Early Stage Cervical Cancer

TypeinterventionalSponsorIstanbul UniversityRan2024 to 2026Enrolled60ConditionsCervical CancersArmsSentinel node biopsy with either ICG or carbon dye injection to cervix
NCT07040657 narecruitingnot on this mapstarted 2025, after this paper: background citation

Comparison of Two-Point and Four-Point Cervical Injection Techniques Using Methylene Blue for Sentinel Lymph Node Mapping in Endometrial Cancer

TypeinterventionalSponsorDokuz Eylul UniversityRan2025 to 2026Enrolled100ConditionsEndometrial Neoplasms, Endometrial Cancer Stage I, Sentinel Lymph Node, MetastasisArmsSentinel Lymph Node Detection/Cervical Methylene Blue Injection
3 · Its place in the literature

Who cites it

141 citing papers in PubMed, 5 syntheses or guidelines pooled it, 400 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Guideline
  4. Pooled it
  5. Pooled it
  6. Trial
  7. Trial
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Review
  17. Cancer of the corpus uteri: A 2025 update.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2025
    Review
  18. Article
  19. Article
  20. Article

81 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 7 institutions in 2 countries.

Robert W HollowayFlorida Hospital Cancer Institute, Orlando, FL, USA. Electronic address: robhollowaymd@gmail.com.
Nadeem R Abu-RustumMemorial Sloan Kettering Cancer Center, New York, NY, USA.
Floor J BackesOhio State University Wexner Medical Center, Columbus, OH, USA.
John F BoggessUniversity of North Carolina, Chapel Hill, NC, USA.
Walter H GotliebJewish General Hospital-McGill University, Montreal, QC, Canada.
W Jeffrey LoweryWalter Reed National Military Medical Center, Bethesda, MD, USA.
Emma C RossiUniversity of North Carolina, Chapel Hill, NC, USA.
Edward J TannerJohns Hopkins Hospital, Kelly Gynecologic Oncology Service, Baltimore, MD, USA.
Rebecca J WolskyUniversity of California at San Francisco, San Francisco, CA, USA.
University of North Carolina at Chapel Hill · USFlorida Hospital Cancer Institute · USJewish General Hospital · CAJohns Hopkins Hospital · USMemorial Sloan Kettering Cancer Center · USThe Ohio State University Wexner Medical Center · USWalter Reed National Military Medical Center · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
Translational Therapeutics Research Program (TT)P30CA016058 · NCI · OHIO STATE UNIVERSITY · PI Tasleem J Padamsee · 1985 to 2026
$132.3M
NCI NIH HHS P30 CA008748NCI NIH HHS P30 CA016058
6 · The paper itself

Abstract

The emphasis in contemporary medical oncology has been "precision" or "personalized" medicine, terms that imply a strategy to improve efficacy through targeted therapies. Similar attempts at precision are occurring in surgical oncology. Sentinel lymph node (SLN) mapping has recently been introduced into the surgical staging of endometrial cancer with the goal to reduce morbidity associated with comprehensive lymphadenectomy, yet obtain prognostic information from lymph node status. The Society of Gynecologic Oncology's (SGO) Clinical Practice Committee and SLN Working Group reviewed the current literature for preparation of this document. Literature-based recommendations for the inclusion of SLN assessment in the treatment of patients with endometrial cancer are presented. This article examines.

Indexed as

Adenocarcinoma, Clear CellCarcinoma, EndometrioidCarcinosarcomaColorimetryColoring AgentsEndometrial NeoplasmsFemaleGynecologyHumansIndocyanine GreenLymph Node ExcisionNeoplasms, Cystic, Mucinous, and SerousNeoplasm StagingOrganotechnetium CompoundsSentinel Lymph NodeSentinel Lymph Node BiopsyColoring AgentsIndocyanine GreenOrganotechnetium CompoundsConsensus recommendationEndometrial cancerLiterature reviewPathology & clinical outcomesSentinel lymph node mappingSurgical staging

Identifiers

PMID28566221
PMCPMC6075736
OpenAlexW2619109410

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

and 2 more above

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.