Evidence map›Paper›PMID 28566000›Full record

ArticleMolecular pain

Peripheral K

Madusha Peiris, James Rf Hockley, David E Reed, Ewan St John Smith, David C Bulmer, L Ashley Blackshaw

Open access · goldAbstract read
In one paragraph

Article in Molecular pain. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 45 citations in OpenAlex.

  1. Review
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  6. KAmerican journal of physiology. Gastrointestinal and liver physiology · 2023
    Article
  7. Article
  8. Article
  9. The Efficacy ofNutrients · 2022
    Article
  10. Opioid-Induced Pronociceptive Signaling in the Gastrointestinal Tract Is Mediated by Delta-Opioid Receptor Signaling.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022
    Article
  11. Beneficial Effects ofFoods (Basel, Switzerland) · 2022
    Article
  12. Article
  13. Flupirtine enhances NHE-3-mediated NaAmerican journal of physiology. Gastrointestinal and liver physiology · 2021
    Article
  14. Activation ofAmerican journal of physiology. Cell physiology · 2021
    Article
  15. Article
  16. Article
  17. Enlightening the frontiers of neurogastroenterology through optogenetics.American journal of physiology. Gastrointestinal and liver physiology · 2020
    Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Madusha Peiris1 Centre for Neuroscience and Trauma, Blizard Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
James Rf Hockley2 Department of Pharmacology, University of Cambridge, Cambridge, UK.
David E Reed3 GI Diseases Research Unit, Queen's University, Kingston, ON, Canada.
Ewan St John Smith2 Department of Pharmacology, University of Cambridge, Cambridge, UK.
David C Bulmer1 Centre for Neuroscience and Trauma, Blizard Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
L Ashley Blackshaw1 Centre for Neuroscience and Trauma, Blizard Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
Queen Mary University of London · GBUniversity of Cambridge · GBQueen's University · CA

Funding

CIHRWellcome Trust
6 · The paper itself

Abstract

Background Chronic visceral pain is a defining symptom of many gastrointestinal disorders. The K

Indexed as

AnimalsAnthracenesColonElectrophysiologyHumansImmunohistochemistryKCNQ3 Potassium ChannelKCNQ Potassium ChannelsMaleMiceMice, Inbred C57BLMyenteric PlexusReceptors, BradykininSensory Receptor CellsSynaptophysin10,10-bis(4-pyridinylmethyl)-9(10H)-anthracenoneAnthracenesKCNQ3 Potassium ChannelKCNQ Potassium ChannelsReceptors, BradykininSynaptophysinKV7retigabine and nociceptionVisceral pain

Identifiers

PMID28566000
PMCPMC5456027
OpenAlexW2620820727

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.