Evidence map›Paper›PMID 28565834›Full record

ArticleExperimental and therapeutic medicine2017

Intravenous infusion umbilical cord-derived mesenchymal stem cell in primary immune thrombocytopenia: A two-year follow-up.

Xiaohua Wang, Xiaoguang Yin, Wei Sun, Jin Bai, Yawen Shen, Qiang Ao, Yongquan Gu, Ying Liu

Registry-linked trialOpen access · diamondAbstract read
In one paragraph

Article in Experimental and therapeutic medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04014166 (Study of Human Umbilical Cord-derived Mesenchymal Stem Cells for Treatment of Refractory Immune Thrombocytopenia), which is not on this map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04014166 nacompletednot on this mapstarted 2019, after this paper: background citation

Study of Human Umbilical Cord-derived Mesenchymal Stem Cells for Treatment of Refractory Immune Thrombocytopenia

TypeinterventionalSponsorInstitute of Hematology & Blood Diseases Hospital, ChinaRan2019 to 2023Enrolled18ConditionsThrombocytopenia, Mesenchymal Stem CellsArmsHuman umbilical cord-derived mesenchymal stem cells (hUC-MSCs)
3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Review
  6. Article
  7. Multipotent mesenchymal stromal/stem cell-based therapies for acute respiratory distress syndrome: current progress, challenges, and future frontiers.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2024
    Review
  8. Article
  9. Review
  10. Article
  11. Review
  12. Review
  13. Review
  14. Article
  15. Article
  16. Article
  17. The Extensive Regulation of MicroRNA in Immune Thrombocytopenia.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Xiaohua WangDepartment of Hematology, Siping Hospital of China Medical University, Siping, Jilin 136000, P.R. China.
Xiaoguang YinJilin Tuhua Bioengineering Company Ltd., Siping, Jilin 136000, P.R. China.
Wei SunDepartment of Hematology, Siping Hospital of China Medical University, Siping, Jilin 136000, P.R. China.
Jin BaiDepartment of Hematology, Siping Hospital of China Medical University, Siping, Jilin 136000, P.R. China.
Yawen ShenDepartment of Hematology, Siping Hospital of China Medical University, Siping, Jilin 136000, P.R. China.
Qiang AoDepartment of Tissue Engineering, China Medical University, Shenyang, Liaoning 110122, P.R. China.
Yongquan GuDepartment of Vascular Surgery, Xuanwu Hospital of Capital Medical University, Beijing 100053, P.R. China.
Ying LiuJilin Tuhua Bioengineering Company Ltd., Siping, Jilin 136000, P.R. China.
China Medical University · CNCapital Medical University · CNJilin Normal University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Four patients with chronic refractory immune thrombocytopenic purpura (ITP) received human umbilical cord-derived mesenchymal stem cells (hUC-MSCs). The hUC-MSC dose was 5×10

Indexed as

chronic immune thrombocytopenic purpuraefficacyhuman umbilical cord-derived mesenchymal stem cellsintravenous infusionsafety

Identifiers

PMID28565834
PMCPMC5443306
OpenAlexW2596214413

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.