ArticlePloS one2017
The Agassiz's desert tortoise genome provides a resource for the conservation of a threatened species.
Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed.
- The genomic basis of independent marine transitions in turtles: convergent episodic adaptation and demographic shifts.Molecular biology and evolution · 2026Article
- Chromosome-level genome assembly of the Chinese soft-shelled turtle Pelodiscus sinensis.Scientific data · 2025Article
- Divergence in Regulatory Regions and Gene Duplications May Underlie Chronobiological Adaptation in Desert Tortoises.Molecular ecology · 2025Article
- A user's guide for understanding reptile and amphibian hydroregulation and climate change impacts.Conservation physiology · 2025Article
- Differential Conservation and Loss of Chicken Repeat 1 (CR1) Retrotransposons in Squamates Reveal Lineage-Specific Genome Dynamics Across Reptiles.Genome biology and evolution · 2024Article
- Multiple horizontal transfer events of a DNA transposon into turtles, fishes, and a frog.Mobile DNA · 2024Article
- Differential Conservation and Loss of CR1 Retrotransposons in Squamates Reveals Lineage-Specific Genome Dynamics across Reptiles.bioRxiv : the preprint server for biology · 2024Article
- Taking advantage of reference-guided assembly in a slowly-evolving lineage: Application to Testudo graeca.PloS one · 2024Article
- Review
- Green, yellow or black? Genetic differentiation and adaptation signatures in a highly migratory marine turtle.Proceedings. Biological sciences · 2021Article
- Article
- Draft Genome of the Common Snapping Turtle,G3 (Bethesda, Md.) · 2020Article
- Article
- Review
- Discovery of a New TLR Gene and Gene Expansion Event through Improved Desert Tortoise Genome Assembly with Chromosome-Scale Scaffolds.Genome biology and evolution · 2020Article
- Immune and sex-biased gene expression in the threatened Mojave desert tortoise, Gopherus agassizii.PloS one · 2020Article
- Transcriptome sequencing reveals signatures of positive selection in the Spot-Tailed Earless Lizard.PloS one · 2020Article
- Body coloration and mechanisms of colour production in Archelosauria: the case of deirocheline turtles.Royal Society open science · 2019Article
- Complex immune responses and molecular reactions to pathogens and disease in a desert reptile (Ecology and evolution · 2019Article
- Article
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9 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Agassiz's desert tortoise (Gopherus agassizii) is a long-lived species native to the Mojave Desert and is listed as threatened under the US Endangered Species Act. To aid conservation efforts for preserving the genetic diversity of this species, we generated a whole genome reference sequence with an annotation based on deep transcriptome sequences of adult skeletal muscle, lung, brain, and blood. The draft genome assembly for G. agassizii has a scaffold N50 length of 252 kbp and a total length of 2.4 Gbp. Genome annotation reveals 20,172 protein-coding genes in the G. agassizii assembly, and that gene structure is more similar to chicken than other turtles. We provide a series of comparative analyses demonstrating (1) that turtles are among the slowest-evolving genome-enabled reptiles, (2) amino acid changes in genes controlling desert tortoise traits such as shell development, longevity and osmoregulation, and (3) fixed variants across the Gopherus species complex in genes related to desert adaptations, including circadian rhythm and innate immune response. This G. agassizii genome reference and annotation is the first such resource for any tortoise, and will serve as a foundation for future analysis of the genetic basis of adaptations to the desert environment, allow for investigation into genomic factors affecting tortoise health, disease and longevity, and serve as a valuable resource for additional studies in this species complex.
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