ReviewPediatrics2017
Adult Consequences of Self-Limited Delayed Puberty.
Review in Pediatrics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
60 citing papers in PubMed, 131 citations in OpenAlex.
- Testosterone therapy in boys with constitutional delay of growth and puberty: a PubMed-based systematic review and exploratory meta-analysis.Clinical and experimental pediatrics · 2026Article
- Ultrasound-based prediction model for years to peak height velocity using multiple secondary ossification centers.Journal of medical ultrasonics (2001) · 2026Article
- Association between parental age at childbirth and timing of puberty in children: an 8-year cohort study.Biology of sex differences · 2026Article
- Pubertal onset in children with in-utero HIV/antiretroviral exposure in Botswana.AIDS (London, England) · 2026Observational
- The endocrine complications of cystic fibrosis.Nature reviews. Endocrinology · 2026Review
- Age at Menarche and Coronary Artery Disease Risk: Divergent Associations With Different Sources of Variation.The Journal of clinical endocrinology and metabolism · 2025Article
- Salivary DNA methylation and pubertal development in adolescents.Scientific reports · 2025Article
- Impact of Puberty on Immune Responses to Mycobacterium tuberculosis in South African Adolescents.The Journal of infectious diseases · 2025Observational
- Pubertal Timing and Health-Related Quality of Life-A Cross-Sectional Study of Polish Adolescents.Pediatric reports · 2025Article
- Deleterious variants in intolerant genes reveal new candidates for self-limited delayed puberty.European journal of endocrinology · 2025Article
- Minimum diet diversity-women score and predictors of school adolescent girl stunting and thinness in Northwest Ethiopia.BMC public health · 2025Article
- Growth Trajectories Over the First Year of Life Among Early-Treated Infants with Human Immunodeficiency Virus and Infants Who are Human Immunodeficiency Virus-Exposed Uninfected.The Journal of pediatrics · 2024Article
- Menarche and Time to Cycle Regularity Among Individuals Born Between 1950 and 2005 in the US.JAMA network open · 2024Article
- Time-varying associations of gestational and childhood triclosan with pubertal and adrenarchal outcomes in early adolescence.Environmental epidemiology (Philadelphia, Pa.) · 2024Article
- Child abuse and pubertal timing: what is the role of child sex and identity of the perpetrator?BMC psychiatry · 2024Article
- Metabolic control of puberty: 60 years in the footsteps of Kennedy and Mitra's seminal work.Nature reviews. Endocrinology · 2024Review
- Self-puberty staging in endocrine encounters during the COVID pandemic.Frontiers in endocrinology · 2024Article
- Invited Perspective: PFAS and Pubertal Timing in Girls-A Maturing Literature.Environmental health perspectives · 2023Article
- Key features of puberty onset and progression can help distinguish self-limited delayed puberty from congenital hypogonadotrophic hypogonadism.Frontiers in endocrinology · 2023Article
- Catch-Up Growth as a Risk Factor for Rapid Weight Gain, Earlier Menarche and Earlier Pubertal Growth Spurt in Girls Born Small for Gestational Age (SGA)-A Longitudinal Study.International journal of environmental research and public health · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Delayed puberty is a common condition defined as the lack of sexual maturation by an age ≥2 SD above the population mean. In the absence of an identified underlying cause, the condition is usually self-limited. Although self-limited delayed puberty is largely believed to be a benign developmental variant with no long-term consequences, several studies have suggested that delayed puberty may in fact have both harmful and protective effects on various adult health outcomes. In particular, height and bone mineral density have been shown to be compromised in some studies of adults with a history of delayed puberty. Delayed puberty may also negatively affect adult psychosocial functioning and educational achievement, and individuals with a history of delayed puberty carry a higher risk for metabolic and cardiovascular disorders. In contrast, a history of delayed puberty appears to be protective for breast and endometrial cancer in women and for testicular cancer in men. Most studies on adult outcomes of self-limited delayed puberty have been in small series with significant variability in outcome measures and study criteria. In this article, we review potential medical and psychosocial issues for adults with a history of self-limited delayed puberty, discuss potential mechanisms underlying these issues, and identify gaps in knowledge and directions for future research.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.