Evidence map›Paper›PMID 28562241›Full record

ArticleeLife2017

Cooperation between a hierarchical set of recruitment sites targets the X chromosome for dosage compensation.

Sarah Elizabeth Albritton, Anna-Lena Kranz, Lara Heermans Winterkorn, Lena Annika Street, Sevinc Ercan

Abstract read
In one paragraph

Article in eLife, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Analysis of developmental gene expression using smFISH andbioRxiv : the preprint server for biology · 2024
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Combinatorial clustering of distinct DNA motifs directs synergistic binding ofProceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  13. Article
  14. The X chromosome in C. elegans sex determination and dosage compensation.Current opinion in genetics & development · 2022
    Review
  15. Review
  16. Article
  17. Article
  18. Binding of anGenetics · 2019
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sarah Elizabeth AlbrittonDepartment of Biology, Center for Genomics and Systems Biology, New York University, New York, United States.ORCID 0000-0001-6093-9560
Anna-Lena KranzDepartment of Biology, Center for Genomics and Systems Biology, New York University, New York, United States.
Lara Heermans WinterkornDepartment of Biology, Center for Genomics and Systems Biology, New York University, New York, United States.
Lena Annika StreetDepartment of Biology, Center for Genomics and Systems Biology, New York University, New York, United States.
Sevinc ErcanDepartment of Biology, Center for Genomics and Systems Biology, New York University, New York, United States.ORCID 0000-0001-7297-1648

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Aric L Daul, Ann E. Rougvie · 2012 to 2026
$7.5M
Mechanisms of X chromosome dosage compensation in C. elegansR01GM107293 · NIGMS · NEW YORK UNIVERSITY · PI ERCAN, SEVINC · 2014 to 2018
$1.5M
NIGMS NIH HHS R01 GM107293NIH HHS P40 OD010440
6 · The paper itself

Abstract

In many organisms, it remains unclear how X chromosomes are specified for dosage compensation, since DNA sequence motifs shown to be important for dosage compensation complex (DCC) recruitment are themselves not X-specific. Here, we addressed this problem in

Indexed as

Dosage Compensation, GeneticAnimalsCaenorhabditis elegansChromatinSyndecan-2X ChromosomeChromatinSyndecan-2C. eleganschromatinchromosomescondensindosage compensationgene regulationgenesgenomics

Identifiers

PMID28562241
PMCPMC5451215

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.