ReviewAccounts of chemical research2017
Ten Good Reasons for the Use of the Tellurium-Centered Anderson-Evans Polyoxotungstate in Protein Crystallography.
Review in Accounts of chemical research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
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Who cites it
39 citing papers in PubMed.
- Data-Driven Polyoxometalate Chemistry.Chemistry (Weinheim an der Bergstrasse, Germany) · 2025Article
- Unravelling 100-Year-Old Mystery of Rosenheim's Transition-Metal Paramolybdate Complexes.Inorganic chemistry · 2025Article
- Tyrosinases: a family of copper-containing metalloenzymes.Chemtexts · 2024Article
- All-Inorganic Polyoxometalates Act as Superchaotropic Membrane Carriers.Advanced materials (Deerfield Beach, Fla.) · 2024Article
- Speciation atlas of polyoxometalates in aqueous solutions.Science advances · 2023Article
- Design, Synthesis, Biological Evaluation, and Crystallographic Study of Novel Purine Nucleoside Phosphorylase Inhibitors.Journal of medicinal chemistry · 2023Article
- Adaptive Responses of a Peroxidase-like Polyoxometalate-Based Tri-Assembly to Bacterial Microenvironment (BME) Significantly Improved the Anti-Bacterial Effects.International journal of molecular sciences · 2023Article
- Exploring the Reactivity of Polyoxometalates toward Proteins: From Interactions to Mechanistic Insights.JACS Au · 2023Review
- Enhancing Protein Crystal Nucleation Using In Situ Templating on Bioconjugate-Functionalized Nanoparticles and Machine Learning.ACS applied materials & interfaces · 2023Article
- Oxo-Replaced Polyoxometalates: There Is More than Oxygen.ACS organic & inorganic Au · 2022Review
- Tellurium-Modified Nucleosides, Nucleotides, and Nucleic Acids with Potential Applications.Molecules (Basel, Switzerland) · 2022Review
- Crystal structures of FNIP/FGxxFN motif-containing leucine-rich repeat proteins.Scientific reports · 2022Article
- Conformational flexibility in the zinc solute-binding protein ZnuA.Acta crystallographica. Section F, Structural biology communications · 2022Article
- A Visual Discrimination of Existing States of Virus Capsid Protein by a Giant Molybdate Cluster.Nanomaterials (Basel, Switzerland) · 2022Article
- Speciation of Transition-Metal-Substituted Keggin-Type Silicotungstates Affected by the Co-crystallization Conditions with Proteinase K.Inorganic chemistry · 2021Article
- Wells-Dawson phosphotungstates as mushroom tyrosinase inhibitors: a speciation study.Scientific reports · 2021Article
- Expanding the reactivity of inorganic clusters towards proteins: the interplay between the redox and hydrolytic activity of Ce(iv)-substituted polyoxometalates as artificial proteases.Chemical science · 2021Article
- Synthesis and characterization of the Anderson-Evans tungstoantimonate [NaActa crystallographica. Section C, Structural chemistry · 2021Article
- Defect {(WInorganic chemistry · 2021Article
- Interweaving Disciplines to Advance Chemistry: Applying Polyoxometalates in Biology.Inorganic chemistry · 2021Review
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2 authors.
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Abstract
Protein crystallography represents at present the most productive and most widely used method to obtain structural information on target proteins and protein-ligand complexes within the atomic resolution range. The knowledge obtained in this way is essential for understanding the biology, chemistry, and biochemistry of proteins and their functions but also for the development of compounds of high pharmacological and medicinal interest. Here, we address the very central problem in protein crystallography: the unpredictability of the crystallization process. Obtaining protein crystals that diffract to high resolutions represents the essential step to perform any structural study by X-ray crystallography; however, this method still depends basically on trial and error making it a very time- and resource-consuming process. The use of additives is an established process to enable or improve the crystallization of proteins in order to obtain high quality crystals. Therefore, a more universal additive addressing a wider range of proteins is desirable as it would represent a huge advance in protein crystallography and at the same time drastically impact multiple research fields. This in turn could add an overall benefit for the entire society as it profits from the faster development of novel or improved drugs and from a deeper understanding of biological, biochemical, and pharmacological phenomena. With this aim in view, we have tested several compounds belonging to the emerging class of polyoxometalates (POMs) for their suitability as crystallization additives and revealed that the tellurium-centered Anderson-Evans polyoxotungstate [TeW
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