ArticleAngewandte Chemie (International ed. in English)2017
Allyl-Palladium-Catalyzed Ketone Dehydrogenation Enables Telescoping with Enone α,β-Vicinal Difunctionalization.
Article in Angewandte Chemie (International ed. in English), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Tandem dehydrogenation-olefination-decarboxylation of cycloalkyl carboxylic acids via multifold C-H activation.Nature communications · 2024Article
- Copper-Catalyzed Decarboxylative Elimination of Carboxylic Acids to Styrenes.The Journal of organic chemistry · 2023Article
- Multiple remote C(spChemical science · 2022Article
- Article
- Synthesis of (-)-melazolide B, a degraded limonoid, from a natural terpene precursor.Tetrahedron chem · 2022Article
- Total Synthesis of Penicibilaenes via C-C Activation-Enabled Skeleton Deconstruction and Desaturation Relay-Mediated C-H Functionalization.Journal of the American Chemical Society · 2021Article
- Dehydrogenative Pd and Ni Catalysis for Total Synthesis.Accounts of chemical research · 2021Review
- Synthesis of (E,E)-Dienones and (E,E)-Dienals via Palladium-Catalyzed γ,δ-Dehydrogenation of Enones and Enals.iScience · 2019Article
- Copper-catalyzed dehydrogenative γ-C(spNature communications · 2019Article
- Palladium-catalyzed α,β-dehydrogenation of acyclic ester equivalents promoted by a novel electron deficient phosphinooxazoline ligand.Tetrahedron · 2019Article
- Total Synthesis of (+)-Granatumine A and Related Bislactone Limonoid Alkaloids via a Pyran to Pyridine Interconversion.Journal of the American Chemical Society · 2019Article
- Allyl-Nickel Catalysis Enables Carbonyl Dehydrogenation and Oxidative Cycloalkenylation of Ketones.Journal of the American Chemical Society · 2019Article
- Vinylidenation of Organoboronic Esters Enabled by a Pd-Catalyzed Metallate Shift.Angewandte Chemie (International ed. in English) · 2019Article
- Total Synthesis of (-)-Xylogranatopyridine B via a Palladium-Catalyzed Oxidative Stannylation of Enones.Journal of the American Chemical Society · 2018Article
- Synthesis of Cyclic Enones by Allyl-Palladium-Catalyzed α,β-Dehydrogenation.Organic letters · 2018Article
- Methylene C(spACS catalysis · 2017Article
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4 authors.
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Abstract
The telescoping of allyl-palladium catalyzed ketone dehydrogenation with organocuprate conjugate addition chemistry allows for the introduction of aryl, heteroaryl, vinyl, acyl, methyl, and other functionalized alkyl groups chemoselectively to a wide variety of unactivated ketone compounds via their enone counterparts. The compatibility of the dehydrogenation conditions additionally allows for efficient trapping of the intermediate enolate with various electrophiles. The utility of this approach is demonstrated by comparison to several previously reported multistep sequences.
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