Evidence map›Paper›PMID 28561801›Full record

ArticleNutrients2017

Is Erythrocyte Protoporphyrin a Better Single Screening Test for Iron Deficiency Compared to Hemoglobin or Mean Cell Volume in Children and Women?

Zuguo Mei, Rafael C Flores-Ayala, Laurence M Grummer-Strawn, Gary M Brittenham

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Observational
  5. Article
  6. Review
  7. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Zuguo MeiDivision of Nutrition, Physical Activity and Obesity, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention (CDC), Atlanta, 30300 GA, USA. zam0@cdc.gov.
Rafael C Flores-AyalaDivision of Nutrition, Physical Activity and Obesity, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention (CDC), Atlanta, 30300 GA, USA. rnf2@cdc.gov.
Laurence M Grummer-StrawnNutrition for Health and Development, World Health Organization (WHO), Geneva 1201, Switzerland. grummerstrawnl@who.int.
Gary M BrittenhamDepartment of Pediatrics, Columbia University, New York, 10032 NY, USA. gmb31@cumc.columbia.edu.
Centers for Disease Control and Prevention · USColumbia University · USWorld Health Organization · CH

Funding

World Health Organization 001
6 · The paper itself

Abstract

Hemoglobin (Hb), mean cell volume (MCV), and erythrocyte protoporphyrin (EP) are commonly used to screen for iron deficiency (ID), but systematic evaluation of the sensitivity and specificity of these tests is limited. The objective of this study is to determine the sensitivity and specificity of Hb, MCV, and EP measurements in screening for ID in preschool children, non-pregnant women 15-49 years of age, and pregnant women. Data from the National Health and Nutrition Examination Surveys (NHANES) (NHANES 2003-2006:

Indexed as

Erythrocyte IndicesAdolescentAdultAnemia, Iron-DeficiencyChild, PreschoolC-Reactive ProteinErythrocytesFemaleFerritinsHemoglobinsHumansIronIron DeficienciesMiddle AgedNutrition SurveysPregnancyC-Reactive ProteinFerritinsHemoglobinsIronProtoporphyrinsReceptors, Transferrinerythrocyte protoporphyrinhemoglobiniron deficiencymean cell volumereceiver operating characteristic curveserum ferritinserum transferrin receptortotal body ironzinc protoporphyrin

Identifiers

PMID28561801
PMCPMC5490536
OpenAlexW2617863086

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.