Evidence map›Paper›PMID 28561744›Full record

ArticleInternational journal of molecular sciences2017

Synthesis and Thrombin, Factor Xa and U46619 Inhibitory Effects of Non-Amidino and Amidino N²-Thiophenecarbonyl- and N²-Tosylanthranilamides.

Soo Hyun Lee, Wonhwa Lee, ThiHa Nguyen, Il Soo Um, Jong-Sup Bae, Eunsook Ma

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Synthesis, crystal structure, Hirshfeld surface analysis, MEP study and mol-ecular docking ofActa crystallographica. Section E, Crystallographic communications · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Soo Hyun LeeCollege of Pharmacy, Catholic University of Daegu, Hayang-ro 13-13, Hayang-eup, Gyeongsan-si, Gyeongbuk 712-702, Korea. Soohyunlee@cu.ac.kr.
Wonhwa LeeCollege of Pharmacy, CMRI, Research Institute of Pharmaceutical Sciences, BK21 Plus KNU Multi-Omics Based Creative Drug Research Team, Kyungpook National University, 80 Daehak-ro, Buk-gu, Daegu 41566, Korea. ByWonhwalee@gmail.com.
ThiHa NguyenCollege of Pharmacy, Catholic University of Daegu, Hayang-ro 13-13, Hayang-eup, Gyeongsan-si, Gyeongbuk 712-702, Korea. Nguyenthiha@gmail.com.
Il Soo UmCollege of Pharmacy, Catholic University of Daegu, Hayang-ro 13-13, Hayang-eup, Gyeongsan-si, Gyeongbuk 712-702, Korea. isu404777@cu.ac.kr.
Jong-Sup BaeCollege of Pharmacy, CMRI, Research Institute of Pharmaceutical Sciences, BK21 Plus KNU Multi-Omics Based Creative Drug Research Team, Kyungpook National University, 80 Daehak-ro, Buk-gu, Daegu 41566, Korea. jongsupbae@gmail.com.
Eunsook MaCollege of Pharmacy, Catholic University of Daegu, Hayang-ro 13-13, Hayang-eup, Gyeongsan-si, Gyeongbuk 712-702, Korea. masook@cu.ac.kr.
Catholic University of Daegu · KRKyungpook National University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thrombin (factor IIa) and factor Xa (FXa) are key enzymes at the junction of the intrinsic and extrinsic coagulation pathways and are the most attractive pharmacological targets for the development of novel anticoagulants. Twenty non-amidino

Indexed as

15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic AcidAnimalsAntithrombinsBlood CoagulationFactor Xa InhibitorsHumansMiceModels, ChemicalMolecular StructureOrganometallic Compoundsortho-AminobenzoatesPartial Thromboplastin TimePlatelet AggregationPlatelet Aggregation InhibitorsProthrombin TimeTriazoles15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid(4-amino-1,4-dihydro-3-(2-pyridyl)-5-thioxo-1,2,4-triazole)copper(II)anthranilamideAntithrombinsFactor Xa InhibitorsOrganometallic Compoundsortho-AminobenzoatesPlatelet Aggregation InhibitorsTriazolesVasoconstrictor Agentsactivated partial thromboplastin timeFactor XaN2-Arylcarbonyl/sulfonylanthranilamidesprothrombin timeThrombinU46619

Identifiers

PMID28561744
PMCPMC5485968
OpenAlexW2594509000

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.