Evidence map›Paper›PMID 28561736›Full record

ArticleeLife2017

A cell cycle-independent, conditional gene inactivation strategy for differentially tagging wild-type and mutant cells.

Sonal Nagarkar-Jaiswal, Sathiya N Manivannan, Zhongyuan Zuo, Hugo J Bellen

Open access · goldAbstract read
In one paragraph

Article in eLife, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 28 citations in OpenAlex.

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  9. Reflections on the use of protein binders to study protein function in developmental biology.Wiley interdisciplinary reviews. Developmental biology · 2019
    Review
  10. AMP-Activated Protein Kinase Regulates Circadian Rhythm by Affecting CLOCK inThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2019
    Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Review
  16. Article
  17. Mosaic Analysis inGenetics · 2018
    Review
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Sonal Nagarkar-JaiswalHoward Hughes Medical Institute, Baylor College of Medicine, Houston, United States.ORCID 0000-0002-2369-3714
Sathiya N ManivannanDepartment of Molecular and Human Genetics, Baylor College of Medicine, Houston, United States.ORCID 0000-0002-9470-2390
Zhongyuan ZuoDepartment of Molecular and Human Genetics, Baylor College of Medicine, Houston, United States.
Hugo J BellenHoward Hughes Medical Institute, Baylor College of Medicine, Houston, United States.ORCID 0000-0001-5992-5989
Baylor College of Medicine · USHoward Hughes Medical Institute · US

Funding

Tumor BiologyP30CA125123 · NCI · BAYLOR COLLEGE OF MEDICINE · PI DAVID R ROWLEY · 2007 to 2026
$73.9M
Transposon induced disruption of most Drosophila genesR01GM067858 · NIGMS · BAYLOR COLLEGE OF MEDICINE · PI BELLEN, HUGO J · 2003 to 2020
$15.7M
Resource Component: Acquisition, maintenance and distribution of Drosophila stocksP40OD018537 · OD · TRUSTEES OF INDIANA UNIVERSITY · PI Annette L. Parks · 2014 to 2026
$13.5M
Steps towards a paternal gene activation therapy for Angelman syndromeU54HD083092 · NICHD · BAYLOR COLLEGE OF MEDICINE · PI NELSON, DAVID LOREN, NEUL, JEFFREY L · 2014 to 2019
$7.8M
Zebrafish CoreU54NS093793 · NINDS · BAYLOR COLLEGE OF MEDICINE · PI BELLEN, HUGO J · 2015 to 2022
$7.5M
Howard Hughes Medical InstituteNCI NIH HHS P30 CA125123NICHD NIH HHS U54 HD083092NIGMS NIH HHS R01 GM067858NIH HHS P40 OD018537NINDS NIH HHS U54 NS093793
6 · The paper itself

Abstract

Here, we describe a novel method based on intronic MiMIC insertions described in Nagarkar-Jaiswal et al. (2015) to perform conditional gene inactivation in

Indexed as

AnimalsDrosophilaGene SilencingGene TargetingLuminescent ProteinsMutagenesis, InsertionalStaining and LabelingLuminescent Proteinsdevelopmental biologyD. melanogastereffeteFLExMiMICneurosciencepost-mitotic cellsSNF4Aγstem cellsTrim9

Identifiers

PMID28561736
PMCPMC5493436
OpenAlexW2617375473

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.