Evidence map›Paper›PMID 28561030›Full record

ArticleNature communications2017

Metabolic network analysis reveals microbial community interactions in anammox granules.

Christopher E Lawson, Sha Wu, Ananda S Bhattacharjee, Joshua J Hamilton, Katherine D McMahon, Ramesh Goel, Daniel R Noguera

Abstract read
In one paragraph

Article in Nature communications, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 113 papers.

0numbers the graph read from it
0cells of the map it votes in
113citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

113 citing papers in PubMed.

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  12. Mutualism between degraders and nondegraders stabilizes the function of a natural biopolymer-degrading community.Proceedings of the National Academy of Sciences of the United States of America · 2025
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53 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Christopher E LawsonDepartment of Civil and Environmental Engineering, University of Wisconsin-Madison, Madison, Wisconsin 53706, USA.
Sha WuDepartment of Civil and Environmental Engineering, University of Utah, Salt Lake City, Utah 84112, USA.
Ananda S BhattacharjeeDepartment of Civil and Environmental Engineering, University of Utah, Salt Lake City, Utah 84112, USA.
Joshua J HamiltonDepartment of Bacteriology, University of Wisconsin-Madison, Madison, Wisconsin 53706, USA.
Katherine D McMahonDepartment of Civil and Environmental Engineering, University of Wisconsin-Madison, Madison, Wisconsin 53706, USA.
Ramesh GoelDepartment of Civil and Environmental Engineering, University of Utah, Salt Lake City, Utah 84112, USA.
Daniel R NogueraDepartment of Civil and Environmental Engineering, University of Wisconsin-Madison, Madison, Wisconsin 53706, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Microbial communities mediating anaerobic ammonium oxidation (anammox) represent one of the most energy-efficient environmental biotechnologies for nitrogen removal from wastewater. However, little is known about the functional role heterotrophic bacteria play in anammox granules. Here, we use genome-centric metagenomics to recover 17 draft genomes of anammox and heterotrophic bacteria from a laboratory-scale anammox bioreactor. We combine metabolic network reconstruction with metatranscriptomics to examine the gene expression of anammox and heterotrophic bacteria and to identify their potential interactions. We find that Chlorobi-affiliated bacteria may be highly active protein degraders, catabolizing extracellular peptides while recycling nitrate to nitrite. Other heterotrophs may also contribute to scavenging of detritus and peptides produced by anammox bacteria, and potentially use alternative electron donors, such as H

Indexed as

Metabolic Networks and PathwaysAmmonium CompoundsBacteriaBioreactorsDenitrificationGenome, BacterialHeterotrophic ProcessesMetagenomicsMicrobial InteractionsNitratesNitritesNitrogenOxidation-ReductionWastewaterWater PurificationAmmonium CompoundsNitratesNitritesNitrogenWastewater

Identifiers

PMID28561030
PMCPMC5460018

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.