Evidence map›Paper›PMID 28561016›Full record

ArticleNature communications2017

Light-driven liquid metal nanotransformers for biomedical theranostics.

Svetlana A Chechetka, Yue Yu, Xu Zhen, Manojit Pramanik, Kanyi Pu, Eijiro Miyako

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 75 papers.

0numbers the graph read from it
0cells of the map it votes in
75citing papers in PubMed
17.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

75 citing papers in PubMed, 441 citations in OpenAlex.

  1. Review
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  11. Liquid Metal-Polyphenol Hybrids for Solar Steam Generation.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
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15 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Svetlana A ChechetkaDepartment of Materials and Chemistry, Nanomaterials Research Institute (NMRI), National Institute of Advanced Industrial Science and Technology (AIST), Central 5, 1-1-1 Higashi, Tsukuba, Ibaraki 305-8565, Japan.
Yue YuDepartment of Materials and Chemistry, Nanomaterials Research Institute (NMRI), National Institute of Advanced Industrial Science and Technology (AIST), Central 5, 1-1-1 Higashi, Tsukuba, Ibaraki 305-8565, Japan.
Xu ZhenSchool of Chemical and Biomedical Engineering, Nanyang Technological University (NTU), Singapore 637457, Singapore.
Manojit PramanikSchool of Chemical and Biomedical Engineering, Nanyang Technological University (NTU), Singapore 637457, Singapore.
Kanyi PuSchool of Chemical and Biomedical Engineering, Nanyang Technological University (NTU), Singapore 637457, Singapore.ORCID 0000-0002-8064-6009
Eijiro MiyakoDepartment of Materials and Chemistry, Nanomaterials Research Institute (NMRI), National Institute of Advanced Industrial Science and Technology (AIST), Central 5, 1-1-1 Higashi, Tsukuba, Ibaraki 305-8565, Japan.
Nanyang Technological University · SGNational Institute of Advanced Industrial Science and Technology · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Room temperature liquid metals (LMs) represent a class of emerging multifunctional materials with attractive novel properties. Here, we show that photopolymerized LMs present a unique nanoscale capsule structure characterized by high water dispersibility and low toxicity. We also demonstrate that the LM nanocapsule generates heat and reactive oxygen species under biologically neutral near-infrared (NIR) laser irradiation. Concomitantly, NIR laser exposure induces a transformation in LM shape, destruction of the nanocapsules, contactless controlled release of the loaded drugs, optical manipulations of a microfluidic blood vessel model and spatiotemporal targeted marking for X-ray-enhanced imaging in biological organs and a living mouse. By exploiting the physicochemical properties of LMs, we achieve effective cancer cell elimination and control of intercellular calcium ion flux. In addition, LMs display a photoacoustic effect in living animals during NIR laser treatment, making this system a powerful tool for bioimaging.

Indexed as

Infrared RaysAnimalsAntineoplastic AgentsBiocompatible MaterialsDrug LiberationFemaleFluorouracilHeLa CellsHumansLasersMaterials TestingMetal NanoparticlesMiceMicrofluidicsModels, AnimalNanocapsulesAntineoplastic AgentsBiocompatible MaterialscarmofurFluorouracilNanocapsulesReactive Oxygen Species

Identifiers

PMID28561016
PMCPMC5460022
OpenAlexW2618330992

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.