ArticleJournal of clinical hypertension (Greenwich, Conn.)2017
Medication compliance and clinical outcomes of fixed-dose combinations vs free combinations of an angiotensin II receptor blocker and a calcium channel blocker in hypertension treatment.
Article in Journal of clinical hypertension (Greenwich, Conn.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Major adverse cardiovascular event definitions used in observational analysis of administrative databases: a systematic review.BMC medical research methodology · 2021Pooled it
- The impact of fixed-dose combination versus free-equivalent combination therapies on adherence for hypertension: a meta-analysis.Journal of clinical hypertension (Greenwich, Conn.) · 2018Pooled it
- Fixed-dose combination pharmacologic therapy to improve hypertension control worldwide: Clinical perspective and policy implications.Journal of clinical hypertension (Greenwich, Conn.) · 2019Trial
- Highlights of the 2026 Korean Society of Hypertension guidelines for the management of hypertension: what's new and what has changed.Clinical hypertension · 2026Review
- The 2022 focused update of the 2018 Korean Hypertension Society Guidelines for the management of hypertension.Clinical hypertension · 2023Review
- Is there any Hope for Monitoring Adherence in an Efficient and Feasible Way for Resistant Hypertension Diagnosis and Follow-Up?Current hypertension reports · 2020Review
- Does the Polypill Improve Patient Adherence Compared to Its Individual Formulations? A Systematic Review.Pharmaceutics · 2020Review
- 2018 Korean Society of Hypertension Guidelines for the management of hypertension: part II-diagnosis and treatment of hypertension.Clinical hypertension · 2019Article
- Long-Term Use of Tamoxifen Is Associated With a Decreased Subsequent Meningioma Risk in Patients With Breast Cancer: A Nationwide Population-Based Cohort Study.Frontiers in pharmacology · 2019Article
- Fixed-dose vs free-dose combinations for the management of hypertension-An analysis of 81 958 patients.Journal of clinical hypertension (Greenwich, Conn.) · 2018Article
- Treatment adherence among adult hypertensive patients: a cross-sectional retrospective study in primary care in Romania.Patient preference and adherence · 2018Article
- Medication compliance and clinical outcomes of fixed-dose combinations vs free combinations of an angiotensin II receptor blocker and a calcium channel blocker in hypertension treatment.Journal of clinical hypertension (Greenwich, Conn.) · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Using the National Health Insurance Research Database of Taiwan, the authors identified 1136 patients taking fixed-dose combination and 4544 patients taking free combinations of an angiotensin II receptor blocker and a dihydropyridine calcium channel blocker from January 2009 to December 2012. At a mean follow-up of 2.1 years, the fixed-dose combination was associated with improved medication adherence and persistence and better survival free from major adverse cardiac events and hospitalization for heart failure compared with the free combination regimens.
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Registered trials
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