Evidence map›Paper›PMID 28560630›Full record

ArticleJournal of neurovirology2017

Diplopia as isolated presentation of varicella zoster central nervous system reactivation.

Cosmo Del Borgo, Valeria Belvisi, Maria Beatrice Valli, Antonio Currà, Irene Pozzetto, Massimiliano Sepe, Claudio Maria Mastroianni

Abstract readCase Reports
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In one paragraph

Article in Journal of neurovirology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 92% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Cosmo Del BorgoInfectious Diseases Unit, S.M. Goretti Hospital, Via Canova 4, 04100, Latina, Italy. cosmodel@tiscali.it.ORCID 0000-0002-7715-1232
Valeria BelvisiInfectious Diseases Unit, S.M. Goretti Hospital, Via Canova 4, 04100, Latina, Italy.
Maria Beatrice ValliLaboratory of Virology, National Institute for Infectious Diseases, "L. Spallanzani", I.R.C.C.S, Rome, Italy.
Antonio CurràAcademic Neurology Unit, A. Fiorini Hospital, Department of Medical-Surgical Sciences and Biotechnologies, Sapienza University of Rome, Terracina, Italy.
Irene PozzettoInfectious Diseases Unit, S.M. Goretti Hospital, Via Canova 4, 04100, Latina, Italy.
Massimiliano SepeOphtalmology Unit, S.M.Goretti Hospital, Latina, Italy.
Claudio Maria MastroianniInfectious Diseases Unit, S.M. Goretti Hospital, Via Canova 4, 04100, Latina, Italy.
Ospedale Santa Maria Goretti · ITIstituto Nazionale per le Malattie Infettive Lazzaro Spallanzani · ITSapienza University of Rome · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Here, we report a patient who developed diplopia secondary to a right cranial nerve III and IV palsy, as well as fever and headache. Cerebrospinal fluid analysis (CSF) showed high varicella-zoster virus (VZV)-DNA viral load (>300,000,000 copies/ml). VZV antibodies in CSF was ≥1:16. Diagnosis of neurological reactivation of VZV infection was made without the presence of characteristic vesicular rash. Quantitative real-time PCR for VZV and intrathecal dosage of VZV IgM and IgG should be performed in cases suspected for viral encephalitis and also in all patients with not otherwise attributable cranial nerve lesions.

Indexed as

Antibodies, ViralCranial Nerve DiseasesDiplopiaDNA, ViralHerpesvirus 3, HumanHerpes ZosterHumansMaleMiddle AgedViral LoadVirus ActivationAntibodies, ViralDNA, ViralDiplopiaVaricella-zoster virus (VZV) reactivation

Identifiers

PMID28560630
OpenAlexW2619244065

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.