Evidence map›Paper›PMID 28560522›Full record

ArticleInflammation research : official journal of the European Histamine Research Society ... [et al.]2017

2-Hydroxy-4-methoxy benzoic acid attenuates the carbon tetra chloride-induced hepatotoxicity and its lipid abnormalities in rats via anti-inflammatory and antioxidant mechanism.

Ghedeir M Alshammari, Aristatile Balakrishnan, Thirunavukkarasu Chinnasamy

Abstract read
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In one paragraph

Article in Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Ghedeir M AlshammariAdipocytes and Metabolic Disorders Lab, Food Science and Nutrition Department, King Saud University, Riyadh, Saudi Arabia. ghedeirksu@gmail.com.
Aristatile BalakrishnanAdipocytes and Metabolic Disorders Lab, Food Science and Nutrition Department, King Saud University, Riyadh, Saudi Arabia.
Thirunavukkarasu ChinnasamyAdipocytes and Metabolic Disorders Lab, Food Science and Nutrition Department, King Saud University, Riyadh, Saudi Arabia. chinnasamyksu@gmail.com.ORCID http://orcid.org/0000-0001-6799-6234
King Saud University · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimLiver inflammation stimulates various inflammatory cytokines and initiates injury through oxidative stress. The aim of this study was to curtaile the liver injury through natural principles such as 2-hydroxy-4-methoxy benzoic acid (HMBA).

methodsThe current study examines the hepatoprotective and lipid lowering effect of HMBA against carbon tetra chloride (CCl

resultsThe hepatoprotective effects of HMBA against CCl

conclusionHMBA is competent of shielding liver from CCl

Indexed as

AnimalsAnti-Inflammatory AgentsAntioxidantsBenzoatesCarbon TetrachlorideChemical and Drug Induced Liver InjuryCollagenCytokinesGlutathioneHeme Oxygenase-1HydroxyprolineLipid MetabolismLipid PeroxidationLiverMalePeroxidase2-hydroxy-4-methoxy benzoic acidAnti-Inflammatory AgentsAntioxidantsBenzoatesCarbon TetrachlorideCollagenCytokinesGlutathioneHeme Oxygenase-1HydroxyprolinePeroxidase2-Hydroxy-4-methoxy benzoic acidAnti-inflammatoryCCl4 toxicityHepatoprotectiveNrf2ROS

Identifiers

PMID28560522
OpenAlexW2618153170

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.