ArticleJournal of biological physics2017
Generation of membrane potential beyond the conceptual range of Donnan theory and Goldman-Hodgkin-Katz equation.
Article in Journal of biological physics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- The need for reconsideration of a mechanism of membrane potential generation using Ling's adsorption theory.European biophysics journal : EBJ · 2021Article
- Discrete Helmholtz model: a single layer of correlated counter-ions. Metal oxides and silica interfaces, ion-exchange and biological membranes.Chemical science · 2020Review
- Mathematical expression of membrane potential based on Ling's adsorption theory is approximately the same as the Goldman-Hodgkin-Katz equation.Journal of biological physics · 2019Article
- Another interpretation of the Goldman-Hodgkin-Katz equation based on Ling's adsorption theory.European biophysics journal : EBJ · 2018Article
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Authors and funding
2 authors.
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Abstract
Donnan theory and Goldman-Hodgkin-Katz equation (GHK eq.) state that the nonzero membrane potential is generated by the asymmetric ion distribution between two solutions separated by a semipermeable membrane and/or by the continuous ion transport across the semipermeable membrane. However, there have been a number of reports of the membrane potential generation behaviors in conflict with those theories. The authors of this paper performed the experimental and theoretical investigation of membrane potential and found that (1) Donnan theory is valid only when the macroscopic electroneutrality is sufficed and (2) Potential behavior across a certain type of membrane appears to be inexplicable on the concept of GHK eq. Consequently, the authors derived a conclusion that the existing theories have some limitations for predicting the membrane potential behavior and we need to find a theory to overcome those limitations. The authors suggest that the ion adsorption theory named Ling's adsorption theory, which attributes the membrane potential generation to the mobile ion adsorption onto the adsorption sites, could overcome those problems.
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