ArticleOsteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA2017
Vertebral fracture in postmenopausal Chinese women: a population-based study.
Article in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 3 of them syntheses that pooled it.
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Who cites it
47 citing papers in PubMed, 3 syntheses or guidelines pooled it, 67 citations in OpenAlex.
- The Prevalence and Risk Factors of Residual Back Pain After Vertebroplasty for Osteoporotic Vertebral Compression Fractures: A Systematic Review and Meta-Analysis.Orthopaedic surgery · 2025Pooled it
- Effects of robot-assisted percutaneous kyphoplasty on osteoporotic vertebral compression fractures: a systematic review and meta-analysis.Journal of robotic surgery · 2024Pooled it
- The prevalence of osteoporotic fractures in the elderly in China: a systematic review and meta-analysis.Journal of orthopaedic surgery and research · 2023Pooled it
- Trial
- Machine learning-based screening model for osteoporosis in Chinese postmenopausal women: a nationwide study with prospective fracture validation.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026Article
- Cost-effectiveness thresholds for initiating osteoporosis treatment in postmenopausal women in China: a microsimulation analysis based on real-world data.Archives of osteoporosis · 2026Article
- Radiographic knee osteoarthritis is associated with higher lumbar spine bone mineral density but not reduced vertebral fracture prevalence: a retrospective cross-sectional study in older Asian women.BMC musculoskeletal disorders · 2026Article
- Associations between abdominal obesity and the prevalence of fractures among Chinese adults: insights from a nationwide cross-sectional study.Frontiers in endocrinology · 2026Article
- CT- and MRI-based endplate osteoporosis status assessment for predicting adjacent vertebral fractures after thoracolumbar percutaneous kyphoplasty: a matched comparison study.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025Article
- Association between obesity and the prevalence of fractures: a population-based cross-sectional study in China.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2025Article
- The prevention of osteoporotic vertebral fractures in eastern and in western countries.Bone reports · 2025Review
- Risk factors of short-term residual low back pain after PKP for the first thoracolumbar osteoporotic vertebral compression fracture.Journal of orthopaedic surgery and research · 2024Article
- A biomechanical investigation comparing a novel bone cement bridging screw system with conventional treatment methods for Kummell's disease.Scientific reports · 2024Article
- Article
- Clinical significance of modified unilateral puncture percutaneous vertebroplasty guided by 3D- printed guides in the treatment of osteoporotic vertebral compression fractures: a retrospective study.BMC musculoskeletal disorders · 2024Article
- A Comparative Study of 2 Techniques to Avoid Bone Cement Loosening and Displacement After Percutaneous Vertebroplasty Treating Unstable Kummell Disease.Neurospine · 2024Article
- Prevalence and risk factors of osteoporotic fracture among the elderly population in China: a multicenter cross-sectional study.International orthopaedics · 2024Article
- Fracture risk prediction in old Chinese people-a narrative review.Archives of osteoporosis · 2023Review
- Influence of Obesity and Changes in Weight or BMI on Incident Fractures in Postmenopausal Women: From Peking Vertebral Fracture Study.Calcified tissue international · 2023Article
- A nomogram for predicting the risk of new vertebral compression fracture after percutaneous kyphoplasty.European journal of medical research · 2023Article
Corrections and comments
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Authors and funding
20 authors at 9 institutions in 2 countries.
Funding
Abstract
In a random sample of postmenopausal Chinese women, the prevalence of radiographic vertebral fractures increased from 13% between ages 50 and 59 to over 50% after age 80 years. A model with seven clinical risk factors predicted the probability of vertebral fractures as well with as without BMD and better than a model with only three risk factors. More than half an hour of outdoor activity per day might correlate with lower risk of vertebral fracture in this population.
introductionWe aimed to describe the prevalence and develop a model for prediction of radiographic vertebral fractures in a large random sample of postmenopausal Chinese women.
methodsWe enrolled 1760 women from an age-stratified random sample of postmenopausal women in Beijing, China. The presence of vertebral fracture was assessed by semi-quantitative grading of lateral thoracolumbar radiographs, risk factors by interview, bone mineral density (BMD) of the proximal femur and lumbar spine by dual x-ray absorptiometry (DXA), and markers of bone turnover from a fasting blood sample. Associations of these factors were analyzed in logistic models and discrimination by areas of receiver operating characteristics curves (AUC).
resultsThe prevalence of vertebral fracture, ranged from 13.4% ages 50 to 59 years old to 58.1% at age 80 years or older. Older age, a history of non-vertebral fracture, lower femoral neck BMD T-score, body mass index (BMI), height loss, housework, and less than half an hour of outdoor activity were significantly associated with increased probability of having a vertebral fracture. A model with those seven factors had a similar AUC with or without BMD and performed better than a simple model with three factors.
conclusionThis study is from a true random sample of postmenopausal women in urban China with high response rate. The prevalence of vertebral fractures in postmenopausal women in Beijing increases from 13% under age 60 to over 50% by age 80 years. A model with seven clinical risk factors with or without BMD is better than simple models and may guide the use of spine x-rays to identify women with vertebral fractures. More than half an hour of outdoor activity might correlate with lower risk of vertebral fracture in this population.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.