ArticleNPJ schizophrenia2017
The effect of cognitive remediation in individuals at ultra-high risk for psychosis: a systematic review.
Article in NPJ schizophrenia, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
38 citing papers in PubMed, 2 syntheses or guidelines pooled it, 87 citations in OpenAlex.
- Longitudinal change in neurocognitive functioning in children and adolescents at clinical high risk for psychosis: a systematic review.European child & adolescent psychiatry · 2024Pooled it
- European Psychiatric Association guidance on assessment of cognitive impairment in schizophrenia.European psychiatry : the journal of the Association of European Psychiatrists · 2022Pooled it
- A randomized controlled trial of Goal Management Training for executive functioning in schizophrenia spectrum disorders or psychosis risk syndromes.BMC psychiatry · 2022Trial
- Understanding Attention in Schizophrenia: The Enduring Influence of Barbara Cornblatt.Schizophrenia bulletin · 2026Review
- Cognitive subtypes in youth at clinical high risk for psychosis.Psychiatry and clinical neurosciences · 2025Article
- Cognitive and Global Morphometry Trajectories as Predictors of Youth Persistent Distressing Psychotic-Like Experiences.Nature. Mental health · 2025Article
- Cognitive Remediation for Psychosis in Virtual Reality (ThinkTactic VR): Qualitative, Iterative, and User-Centered Codevelopment Study.JMIR mental health · 2025Article
- Abnormalities in cognitive-related functional connectivity can be used to identify patients with schizophrenia and individuals in clinical high-risk.BMC psychiatry · 2025Article
- Tunisian Adolescents at CHR for Psychosis: A Pilot Study of Cognitive Remediation in a LMIC.Early intervention in psychiatry · 2025Article
- Improving processing speed in adolescents at clinical high risk for psychosis with the Specific COgnitive REmediation plus Surround (SCORES) intervention: Study protocol.Early intervention in psychiatry · 2025Article
- Delivery of Neuropsychological Interventions for Adult and Older Adult Clinical Populations: An Australian Expert Working Group Clinical Guidance Paper.Neuropsychology review · 2024Review
- Treating Cognition in Schizophrenia: A Whole Lifespan Perspective.Healthcare (Basel, Switzerland) · 2024Review
- Working memory performance is related to childhood trauma but not psychotic-like experiences in a nonpsychiatric sample.Psychological trauma : theory, research, practice and policy · 2024Article
- Article
- Correlations between Negative Symptoms and Cognitive Deficits in Individuals at First Psychotic Episode or at High Risk of Psychosis: A Systematic Review.Journal of clinical medicine · 2023Review
- Developmental trajectories of premorbid functioning predict cognitive remediation treatment response in first-episode schizophrenia.Psychological medicine · 2023Article
- Cognitive Impairments and Rehabilitation in Individuals with at-Risk Mental State for Psychosis.Journal of personalized medicine · 2023Article
- Neurocognition and functioning in adolescents at clinical high risk for psychosis.Child and adolescent psychiatry and mental health · 2023Article
- Feasibility and effect of an immersive virtual reality-based platform for cognitive training in real-life scenarios in patients with mood - or psychotic disorders: A randomized, controlled proof-of-concept study.Neuroscience applied · 2023Article
- Elucidating gut microbiota-hippocampus interactions in emerging psychosis: A new perspective for the development of early interventions for memory impairments.Frontiers in psychiatry · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cognitive deficits are prominent features of the ultra-high risk state for psychosis that are known to impact functioning and course of illness. Cognitive remediation appears to be the most promising treatment approach to alleviate the cognitive deficits, which may translate into functional improvements. This study systematically reviewed the evidence on the effectiveness of cognitive remediation in the ultra-high risk population. The electronic databases MEDLINE, PsycINFO, and Embase were searched using keywords related to cognitive remediation and the UHR state. Studies were included if they were peer-reviewed, written in English, and included a population meeting standardized ultra-high risk criteria. Six original research articles were identified. All the studies provided computerized, bottom-up-based cognitive remediation, predominantly targeting neurocognitive function. Four out of five studies that reported a cognitive outcome found cognitive remediation to improve cognition in the domains of verbal memory, attention, and processing speed. Two out of four studies that reported on functional outcome found cognitive remediation to improve the functional outcome in the domains of social functioning and social adjustment. Zero out of the five studies that reported such an outcome found cognitive remediation to affect the magnitude of clinical symptoms. Research on the effect of cognitive remediation in the ultra-high risk state is still scarce. The current state of evidence indicates an effect of cognitive remediation on cognition and functioning in ultra-high risk individuals. More research on cognitive remediation in ultra-high risk is needed, notably in large-scale trials assessing the effect of neurocognitive and/or social cognitive remediation on multiple outcomes.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.