Evidence map›Paper›PMID 28560264›Full record

ArticleNPJ schizophrenia2017

Thought disorder measured as random speech structure classifies negative symptoms and schizophrenia diagnosis 6 months in advance.

Natália B Mota, Mauro Copelli, Sidarta Ribeiro

Open access · goldAbstract read
In one paragraph

Article in NPJ schizophrenia, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
67citing papers in PubMed, 3 pooled it
7.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

67 citing papers in PubMed, 3 syntheses or guidelines pooled it, 166 citations in OpenAlex.

  1. Pooled it
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  14. New strategies for the cognitive science of dreaming.Trends in cognitive sciences · 2024
    Review
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  20. Trajectories through semantic spaces in schizophrenia and the relationship to ripple bursts.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article

7 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Natália B MotaBrain Institute, Federal University of Rio Grande do Norte, UFRN, Natal, RN Brazil.
Mauro CopelliPhysics Department, Federal University of Pernambuco, UFPE, Recife, PE Brazil.
Sidarta RibeiroBrain Institute, Federal University of Rio Grande do Norte, UFRN, Natal, RN Brazil.
Universidade Federal do Rio Grande do Norte · BRUniversidade Federal de Pernambuco · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In chronic psychotic patients, word graph analysis shows potential as complementary psychiatric assessment. This analysis relies mostly on connectedness, a structural feature of speech that is anti-correlated with negative symptoms. Here we aimed to verify whether speech disorganization during the first clinical contact, as measured by graph connectedness, can correctly classify negative symptoms and the schizophrenia diagnosis 6 months in advance. Positive and negative syndrome scale scores and memory reports were collected from 21 patients undergoing first clinical contact for recent-onset psychosis, followed for 6 months to establish diagnosis, and compared to 21 well-matched healthy subjects. Each report was represented as a word-trajectory graph. Connectedness was measured by number of edges, number of nodes in the largest connected component and number of nodes in the largest strongly connected component. Similarities to random graphs were estimated. All connectedness attributes were combined into a single Disorganization Index weighted by the correlation with the positive and negative syndrome scale negative subscale, and used for classifications. Random-like connectedness was more prevalent among schizophrenia patients (64 × 5% in Control group,

Identifiers

PMID28560264
PMCPMC5441540
OpenAlexW2604132829

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.