Evidence map›Paper›PMID 28560183›Full record

ArticleFrontiers in cellular and infection microbiology2017

Outbreak by Hypermucoviscous

Lingling Zhan, Shanshan Wang, Yinjuan Guo, Ye Jin, Jingjing Duan, Zhihao Hao, Jingnan Lv, Xiuqin Qi, Longhua Hu, Liang Chen and 5 more

Registry-linked trialAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05932355 (Assessment of the Effect of Plasmid Inhibitors and Antimicrobial Drugs as Combined Strategy Against Clinical Multi-drug Resistant Hypervirulent Klebsiella Pneumoniae), which is not on this map. Cited by 115 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
115citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05932355 unknown statusnot on this mapstarted 2023, after this paper: background citation

Assessment of the Effect of Plasmid Inhibitors and Antimicrobial Drugs as Combined Strategy Against Clinical Multi-drug Resistant Hypervirulent Klebsiella Pneumoniae

TypeobservationalSponsorAssiut UniversityRan2023 to 2025Enrolled50ConditionsSynergy Between Plasmid Inhibitors and Combined Antibiotics
3 · Its place in the literature

Who cites it

115 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Genomic Analysis of HypervirulentIranian journal of biotechnology · 2026
    Article
  6. Connections betweenInfection and immunity · 2026
    Article
  7. Hypervirulent and Drug-ResistantInternational journal of general medicine · 2026
    Review
  8. Co-evolution of resistance and virulence inFrontiers in cellular and infection microbiology · 2026
    Review
  9. Article
  10. Multiplex PCR assay for the rapid detection ofJournal of medical microbiology · 2025
    Article
  11. Lineage-specific evolution and resistance-virulence divergence inAntimicrobial agents and chemotherapy · 2025
    Article
  12. Article
  13. Molecular and genetic features of a blaAnnals of clinical microbiology and antimicrobials · 2025
    Article
  14. Review
  15. Hypervirulent Carbapenem-resistantInfection and drug resistance · 2025
    Review
  16. Article
  17. Article
  18. Review
  19. Molecular and epidemiological characterization of carbapenem-resistant hypervirulentFrontiers in cellular and infection microbiology · 2025
    Article
  20. Article

55 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Lingling ZhanDepartment of Laboratory Medicine, The First Affiliated Hospital of Wenzhou Medical UniversityWenzhou, China.
Shanshan WangDepartment of Laboratory Medicine, The First Affiliated Hospital of Wenzhou Medical UniversityWenzhou, China.
Yinjuan GuoDepartment of Laboratory Medicine, The First Affiliated Hospital of Wenzhou Medical UniversityWenzhou, China.
Ye JinDepartment of Laboratory Medicine, The First Affiliated Hospital of Wenzhou Medical UniversityWenzhou, China.
Jingjing DuanDepartment of Laboratory Medicine, The First Affiliated Hospital of Wenzhou Medical UniversityWenzhou, China.
Zhihao HaoDepartment of Laboratory Medicine, The First Affiliated Hospital of Wenzhou Medical UniversityWenzhou, China.
Jingnan LvDepartment of Laboratory Medicine, The First Affiliated Hospital of Wenzhou Medical UniversityWenzhou, China.
Xiuqin QiDepartment of Laboratory Medicine, The First Affiliated Hospital of Wenzhou Medical UniversityWenzhou, China.
Longhua HuDepartment of Laboratory Medicine, The Second Affiliated Hospital of Nanchang UniversityNanchang, China.
Liang ChenPublic Health Research Institute Tuberculosis Center, New Jersey Medical School, Rutgers UniversityNewark, NJ, USA.
Barry N KreiswirthPublic Health Research Institute Tuberculosis Center, New Jersey Medical School, Rutgers UniversityNewark, NJ, USA.
Rong ZhangDepartment of Laboratory Medicine, The Second Affiliated Hospital of Zhejiang UniversityHangzhou, China.
Jingye PanDepartment of Intensive Care Unit, The First Affiliated Hospital of Wenzhou Medical UniversityWenzhou, China.
Liangxing WangDepartment of Respiratory Medicine, The First Affiliated Hospital of Wenzhou Medical UniversityWenzhou, China.
Fangyou YuDepartment of Laboratory Medicine, The First Affiliated Hospital of Wenzhou Medical UniversityWenzhou, China.

Funding

The molecular basis of the epidemic blaKPC gene KlebsiellaR01AI090155 · NIAID · UNIV OF MED/DENT OF NJ-NJ MEDICAL SCHOOL · PI KREISWIRTH, BARRY NEAL · 2011 to 2021
$7.2M
Genomic variation in epidemic carbapenem-resistant K.pneumoniaeR21AI117338 · NIAID · RBHS-NEW JERSEY MEDICAL SCHOOL · PI CHEN, LIANG · 2016 to 2017
$437k
NIAID NIH HHS R01 AI090155NIAID NIH HHS R21 AI117338
6 · The paper itself

Abstract

Hypervirulent and multidrug resistant

Indexed as

Disease OutbreaksTertiary Care CentersAdultAgedAged, 80 and overAnti-Bacterial AgentsBacterial Capsulesbeta-LactamasesCarbapenem-Resistant EnterobacteriaceaeChinaDrug Resistance, Multiple, BacterialFemaleHumansKlebsiella InfectionsKlebsiella pneumoniaeMaleAnti-Bacterial Agentsbeta-lactamase KPC-2, Klebsiella pneumoniaebeta-Lactamasescarbapenem resistanceepidemiologyhypermucoviscousKlesiella pneumoniaeKPC-2

Identifiers

PMID28560183
PMCPMC5432538

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.