ArticleNeuroImage. Clinical2017
Application of calibrated fMRI in Alzheimer's disease.
Open access · goldAbstract read
In one paragraph
Article in NeuroImage. Clinical, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 2 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 2 pooled it
3.6field-weighted citation impact, top 7% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 2 syntheses or guidelines pooled it, 64 citations in OpenAlex.
- Altered cerebral blood flow in older adults with Alzheimer's disease: a systematic review.Brain imaging and behavior · 2023Pooled it
- Cerebrovascular Reactivity Measurement Using Magnetic Resonance Imaging: A Systematic Review.Frontiers in physiology · 2021Pooled it
- The effect of risperidone on reward-related brain activity is robust to drug-induced vascular changes.Human brain mapping · 2021Trial
- Assessing subcortical, brainstem and cerebellar metabolic patterns using [18F]FDG PET-CT imaging in dementia with Lewy bodies.European journal of nuclear medicine and molecular imaging · 2026Article
- Graphomotor performance as a quantitative marker of Alzheimer's disease: a tablet-based case-control ROC study.Frontiers in neuroscience · 2026Article
- Neuronal plasticity and its role in Alzheimer's disease and Parkinson's disease.Neural regeneration research · 2026Article
- A short investigation of the effect of the selection of human brain atlases on the performance of ASD's classification models.Frontiers in neuroscience · 2025Review
- MAMs and Mitochondrial Quality Control: Overview and Their Role in Alzheimer's Disease.Neurochemical research · 2024Review
- ASD-GANNet: A Generative Adversarial Network-Inspired Deep Learning Approach for the Classification of Autism Brain Disorder.Brain sciences · 2024Article
- Neurovascular coupling is optimized to compensate for the increase in proton production from nonoxidative glycolysis and glycogenolysis during brain activation and maintain homeostasis of pH, pCOJournal of neurochemistry · 2024Article
- Automatic Rejection based on Tissue Signal (ARTS) for motion-corrected quantification of cerebral venous oxygenation in neonates and older adults.Magnetic resonance imaging · 2024Article
- fMRI-based Alzheimer's disease detection via functional connectivity analysis: a systematic review.PeerJ. Computer science · 2024Article
- Cerebral oxygen metabolism from MRI susceptibility.NeuroImage · 2023Review
- Biomarkers of aging.Science China. Life sciences · 2023Review
- Article
- Cerebral oxygen extraction fraction MRI: Techniques and applications.Magnetic resonance in medicine · 2022Review
- Mapping oxidative metabolism in the human brain with calibrated fMRI in health and disease.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2022Article
- A flow-diffusion model of oxygen transport for quantitative mapping of cerebral metabolic rate of oxygen (CMROJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2022Article
- Aerobic glycolysis imaging of epileptic foci during the inter-ictal period.EBioMedicine · 2022Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
17 authors at 8 institutions in 2 countries.
Isabelle LajoieDépartement de Pharmacologie et physiologie, Université de Montréal, Montreal, QC, Canada; Centre de Recherche de l'Institut Universitaire de Gériatrie de Montréal, Montreal, QC, Canada; Montreal Neurological Institute, Montreal, QC, Canada. Electronic address: isabelle.lajoie@mail.mcgill.ca.
Scott NugentCentre de Recherche de l'Institut Universitaire de Gériatrie de Montréal, Montreal, QC, Canada; Montreal Neurological Institute, Montreal, QC, Canada; Department of Neurology and Neurosurgery, McGill University, Montreal, QC, Canada.
Clément DebackerCentre de Recherche de l'Institut Universitaire de Gériatrie de Montréal, Montreal, QC, Canada; Montreal Neurological Institute, Montreal, QC, Canada; Department of Psychiatry, McGill University, Montreal, QC, Canada.
Kenneth DysonCentre de Recherche de l'Institut Universitaire de Gériatrie de Montréal, Montreal, QC, Canada; Montreal Neurological Institute, Montreal, QC, Canada; Department of Physiology, McGill University, Montreal, QC, Canada.
Felipe B TancrediDepartamento de Radiologia, Centro de Pesquisa em Imagem, Hospital Israelita Albert Einstein, São Palo, SP, Brazil.
AmanPreet BadhwarCentre de Recherche de l'Institut Universitaire de Gériatrie de Montréal, Montreal, QC, Canada; Department of Computer Science and Operations Research, Université de Montréal, Montreal, QC, Canada.
Sylvie BellevilleCentre de Recherche de l'Institut Universitaire de Gériatrie de Montréal, Montreal, QC, Canada; Département de Psychologie, Université de Montréal, Montreal, QC, Canada.
Yan DeschaintreDépartement de Neurosciences, Université de Montréal, Montreal, QC, Canada; Service de neurologie, Département de Médecine, CHUM Notre-Dame, Montréal, QC, Canada.
Pierre BellecCentre de Recherche de l'Institut Universitaire de Gériatrie de Montréal, Montreal, QC, Canada; Department of Computer Science and Operations Research, Université de Montréal, Montreal, QC, Canada.
Julien DoyonCentre de Recherche de l'Institut Universitaire de Gériatrie de Montréal, Montreal, QC, Canada; Département de Psychologie, Université de Montréal, Montreal, QC, Canada.
Christian BoctiDivision de Neurologie, Faculté de Médecine et des Sciences de la Santé & Research Centre on Aging, Université de Sherbrooke, Sherbrooke, QC, Canada.
Serge GauthierMcGill Center for Studies in Aging, Douglas Mental Health Research Institute, Montreal, QC, Canada.
Douglas ArnoldMontreal Neurological Institute, Montreal, QC, Canada; Department of Neurology and Neurosurgery, McGill University, Montreal, QC, Canada.
Marie-Jeanne KergoatCentre de Recherche de l'Institut Universitaire de Gériatrie de Montréal, Montreal, QC, Canada; Département de Médecine, Université de Montréal, Montreal, QC, Canada.
Howard ChertkowCentre de Recherche de l'Institut Universitaire de Gériatrie de Montréal, Montreal, QC, Canada; Department of Neurology and Neurosurgery, McGill University, Montreal, QC, Canada; Department of Medicine, Sir Mortimer B. Davis-Jewish General Hospital, McGill University, Montreal, QC, Canada.
Oury MonchiCentre de Recherche de l'Institut Universitaire de Gériatrie de Montréal, Montreal, QC, Canada; Department of Neurology and Neurosurgery, McGill University, Montreal, QC, Canada; McGill Center for Studies in Aging, Douglas Mental Health Research Institute, Montreal, QC, Canada; Department of Clinical Neurosciences and Hotchkiss Brain Institute, University of Calgary, Calgary, AB, Canada.
Richard D HogeDépartement de Pharmacologie et physiologie, Université de Montréal, Montreal, QC, Canada; Centre de Recherche de l'Institut Universitaire de Gériatrie de Montréal, Montreal, QC, Canada; Montreal Neurological Institute, Montreal, QC, Canada; Department of Neurology and Neurosurgery, McGill University, Montreal, QC, Canada.
Montreal Neurological Institute and Hospital · CAInstitut Universitaire de Gériatrie de Montréal · CADouglas Mental Health University Institute · CAHôpital Notre-Dame · CAHospital Israelita Albert Einstein · BRJewish General Hospital · CAUniversité de Sherbrooke · CAUniversity of Calgary · CA
Funding
CIHR MOP 123492
Abstract
Calibrated fMRI based on arterial spin-labeling (ASL) and blood oxygen-dependent contrast (BOLD), combined with periods of hypercapnia and hyperoxia, can provide information on cerebrovascular reactivity (CVR), resting blood flow (CBF), oxygen extraction fraction (OEF), and resting oxidative metabolism (CMRO
Indexed as
AgedAged, 80 and overAlzheimer DiseaseCalibrationCerebrovascular CirculationFemaleFunctional NeuroimagingHumansMagnetic Resonance ImagingMaleOxygenSpin LabelsOxygenSpin LabelsAlzheimer's diseaseBOLD calibration constantCalibrated fMRICerebral blood flowCerebrovascular reactivityOxidative metabolismOxygen extraction fraction
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.