Evidence map›Paper›PMID 28560127›Full record

ArticleCureus2017

Naproxen and Diclofenac Attenuate Atorvastatin-induced Preconditioning of the Myocardium.

Zoltan Varga, Martina Nemcekova, Slavka Carnicka, Veronika Slezakova, Miriam Petrova, Marek Majdan, Tana Ravingerova, Viera Kristova

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cureus, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 94% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Zoltan VargaInternal Medicine Residency, Florida Hospital Orlando.
Martina NemcekovaInstitute for Heart Research, Slovak Academy of Sciences.
Slavka CarnickaInstitute for Heart Research, Slovak Academy of Sciences.
Veronika SlezakovaDepartment of Pharmacology and Clinical Pharmacology, Comenius University in Bratislava.
Miriam PetrovaDepartment of Pharmacology and Clinical Pharmacology, Comenius University in Bratislava.
Marek MajdanDepartment of Public Health, Trnava University.
Tana RavingerovaInstitute for Heart Research, Slovak Academy of Sciences.
Viera KristovaDepartment of Pharmacology and Clinical Pharmacology, Comenius University in Bratislava.
University of Trnava · SKComenius University Bratislava · SKAdventHealth Orlando · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Statins reduce infarct size (IS) in ischemia-reperfusion injury of the myocardium. Inhibition of cyclooxygenase-2 (COX-2) attenuates this benefit. We investigated the effect of two widely used non-selective non-steroidal anti-inflammatory drugs (NSAIDs) with different degree of anti-COX-2 activity on atorvastatin-mediated preconditioning. Wistar rats received oral atorvastatin (10 mg∙kg

Indexed as

atorvastatincyclooxygenase-2diclofenacmyocardial infarctionnaproxenpreconditioning

Identifiers

PMID28560127
PMCPMC5446225
OpenAlexW2609260393

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.