Evidence map›Paper›PMID 28560089›Full record

ArticleBioResearch open access2017

Characterization of a Murine Model of Bioequivalent Bladder Wound Healing and Repair Following Subtotal Cystectomy.

Mona Zarifpour, Karl-Erik Andersson, Sneha S Kelkar, Aaron Mohs, Cathy Mendelsohn, Kerry Schneider, Frank Marini, George J Christ

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BioResearch open access, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 92% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Mona ZarifpourWake Forest Institute for Regenerative Medicine, Winston-Salem, North Carolina.
Karl-Erik AnderssonWake Forest Institute for Regenerative Medicine, Winston-Salem, North Carolina.
Sneha S KelkarWake Forest Institute for Regenerative Medicine, Winston-Salem, North Carolina.
Aaron MohsWake Forest Institute for Regenerative Medicine, Winston-Salem, North Carolina.
Cathy MendelsohnDepartment of Urology, Pathology and Cell Biology, Genetics and Development, Columbia University, New York, New York.
Kerry SchneiderDepartment of Urology, Pathology and Cell Biology, Genetics and Development, Columbia University, New York, New York.
Frank MariniWake Forest Institute for Regenerative Medicine, Winston-Salem, North Carolina.
George J ChristWake Forest Institute for Regenerative Medicine, Winston-Salem, North Carolina.
Forest Institute · USCancer Genetics (United States) · US

Funding

Regeneration, Repair and Remodeling of the Lower Urinary Tract P20DK097806 · NIDDK · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI MARINI, FRANK C. · 2012 to 2015
$1.5M
NIDDK NIH HHS P20 DK097806
6 · The paper itself

Abstract

Previous work demonstrated restoration of a bioequivalent bladder within 8 weeks of removing the majority of the bladder (subtotal cystectomy or STC) in rats. The goal of the present study was to extend our investigations of bladder repair to the murine model, to harness the power of mouse genetics to delineate the cellular and molecular mechanisms responsible for the observed robust bladder regrowth. Female C57 black mice underwent STC, and at 4, 8, and 12 weeks post-STC, bladder repair and function were assessed via cystometry,

Indexed as

bladdermurineregenerationrepairsubtotal cystectomywound healing

Identifiers

PMID28560089
PMCPMC5439456
OpenAlexW2610571663

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.