Evidence map›Paper›PMID 28559967›Full record

ArticleAmerican journal of translational research2017

Effect of activation of Toll-like receptor 7 in the inhibition of allergic asthma on a mouse model.

Li Ma, Xiaojun Xiao, Yihe Ma, Haiqiang Wu, Shuqi Qiu, Jing Li, Pingchang Yang, Zhigang Liu

Open access · greenAbstract read
PubMed Full text at PMC
In one paragraph

Article in American journal of translational research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Allergen immunotherapy in China.Frontiers in allergy · 2023
    Review
  2. Review
  3. Targeting Antiviral Pathways for Treatment of Allergic Diseases.Journal of the Pediatric Infectious Diseases Society · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Li MaThe State Key Laboratory of Respiratory Disease for Allergy at Shengzhen University, School of Medicine, Shenzhen UniversityShenzhen 518116, China.
Xiaojun XiaoThe State Key Laboratory of Respiratory Disease for Allergy at Shengzhen University, School of Medicine, Shenzhen UniversityShenzhen 518116, China.
Yihe MaThe State Key Laboratory of Respiratory Disease for Allergy at Shengzhen University, School of Medicine, Shenzhen UniversityShenzhen 518116, China.
Haiqiang WuThe State Key Laboratory of Respiratory Disease for Allergy at Shengzhen University, School of Medicine, Shenzhen UniversityShenzhen 518116, China.
Shuqi QiuShenzhen Key Laboratory of ENT, Institute of ENT & Longgang ENT HospitalShenzhen 518172, China.
Jing LiState Key Laboratory of Respiratory Disease, Guangzhou Medical CollegeGuangzhou 510006, China.
Pingchang YangThe State Key Laboratory of Respiratory Disease for Allergy at Shengzhen University, School of Medicine, Shenzhen UniversityShenzhen 518116, China.
Zhigang LiuThe State Key Laboratory of Respiratory Disease for Allergy at Shengzhen University, School of Medicine, Shenzhen UniversityShenzhen 518116, China.
Shenzhen University · CNLonggang Central Hospital · CNState Key Laboratory of Respiratory Disease · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Targeting Toll-like receptor 7 (TLR7) is known to have a potential therapeutic effect on experimental allergic asthma, but the exact mechanism is incompletely understood. To investigate the potential therapeutic effect of TLR7 agonist (TLR7a) a new versatile TLR7 agonist conjugated to Der f 1 was synthesized and evaluated

Indexed as

adjuvantAllergic asthmaDer f-1dust miteimmunotherapyTLR7 agonist

Identifiers

PMID28559967
PMCPMC5446499
OpenAlexW2621015467

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.