Evidence map›Paper›PMID 28559919›Full record

ArticleJournal of occupational medicine and toxicology (London, England)2017

Prevalence of latent tuberculosis infection among foreign students in Lübeck, Germany tested with QuantiFERON-TB Gold In-Tube and QuantiFERON-TB Gold Plus.

Elia Noemi Gallegos Morales, Johannes Knierer, Anja Schablon, Albert Nienhaus, Jan Felix Kersten

Open access · goldAbstract read
In one paragraph

Article in Journal of occupational medicine and toxicology (London, England), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 3 pooled it
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 3 syntheses or guidelines pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Comparing the Diagnostic Performance of QuantiFERON-TB Gold Plus to Other Tests of Latent Tuberculosis Infection: A Systematic Review and Meta-analysis.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2021
    Pooled it
  4. Article
  5. Review
  6. Risk Analysis of Latent Tuberculosis Infection among Health Workers Compared to Employees in Other Sectors.International journal of environmental research and public health · 2020
    Article
  7. Article
  8. Article
  9. Descriptive review of junior OB/GYN physicians' work task financial compensation in German hospitals.Journal of occupational medicine and toxicology (London, England) · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Elia Noemi Gallegos MoralesCenter of Excellence for Health Services Research in Nursing (CVcare), University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany.
Johannes KniererCenter of Excellence for Health Services Research in Nursing (CVcare), University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany.
Anja SchablonCenter of Excellence for Health Services Research in Nursing (CVcare), University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany.
Albert NienhausCenter of Excellence for Health Services Research in Nursing (CVcare), University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany.
Jan Felix KerstenCenter of Excellence for Health Services Research in Nursing (CVcare), University Medical Center Hamburg-Eppendorf (UKE), Hamburg, Germany.
Universität Hamburg · DEUniversity Medical Center Hamburg-Eppendorf · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe tuberculosis (TB) incidence rate in foreign-born individuals has been increasing in Germany in recent years. Foreign students may be an important source of latent tuberculosis infection (LTBI) in low-incidence countries. In Germany, there are no guidelines for LTBI screening of foreign students. The aim of the study was to estimate LTBI prevalence and evaluate associated risk factors among foreign students in Germany. The second purpose of our study was to compare the results of the new generation of QuantiFERON-TB Gold Plus (QFT-Plus) to those of its predecessor QuantiFERON-TB Gold In-Tube (QFT-GIT).

methodsThis cross

resultsOne hundred thirty four students participated in the study. The overall prevalence as regards positive results from both tests, QFT-Plus and QFT-GIT, was 9.7%, and the prevalence of positive QFT-Plus results was 8.2%. The main independent variables associated with a positive QFT-Plus result were a) being born in a high-incidence country (OR = 6.7, 95% CI: 1.3-34.3) and b) previous contact with a person with active TB (OR = 4.5, 95% CI: 1.1-18.3). Higher age (OR = 2.8, 95% CI: 0.7-11.3) and male gender (OR = 1.6, 95% CI: 0.4-6.7) showed a tendency toward positive QFT-Plus results but this was not statistically significant. Agreement between QFT-Plus and QFT-GIT results was κ = 0.85,

conclusionsThe LTBI prevalence among foreign students was about 10%. We recommend implementing a policy whereby all foreign students are screened by means of a questionnaire about LTBI risk factors, so that only students with present risk factors are tested for LTBI. The agreement between the new QFT-Plus and the QFT-GIT (κ = 0.85) was good. QFT-Plus might be used in the same format as its predecessor.

Indexed as

Foreign studentsLatent tuberculosis infectionQuantiFERON-TB Gold PlusRisk factors

Identifiers

PMID28559919
PMCPMC5445359
OpenAlexW2619985068

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.