Evidence map›Paper›PMID 28559850›Full record

ReviewFrontiers in physiology2017

Innovative Perspective: Gadolinium-Free Magnetic Resonance Imaging in Long-Term Follow-Up after Kidney Transplantation.

Mick J M van Eijs, Arjan D van Zuilen, Anneloes de Boer, Martijn Froeling, Tri Q Nguyen, Jaap A Joles, Tim Leiner, Marianne C Verhaar

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Update on imaging-based diagnosis of acute renal allograft rejection.American journal of nuclear medicine and molecular imaging · 2019
    Review
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Mick J M van EijsDepartment of Nephrology and Hypertension, University Medical Center UtrechtUtrecht, Netherlands.
Arjan D van ZuilenDepartment of Nephrology and Hypertension, University Medical Center UtrechtUtrecht, Netherlands.
Anneloes de BoerDepartment of Radiology, University Medical Center UtrechtUtrecht, Netherlands.
Martijn FroelingDepartment of Radiology, University Medical Center UtrechtUtrecht, Netherlands.
Tri Q NguyenDepartment of Pathology, University Medical Center UtrechtUtrecht, Netherlands.
Jaap A JolesDepartment of Nephrology and Hypertension, University Medical Center UtrechtUtrecht, Netherlands.
Tim LeinerDepartment of Radiology, University Medical Center UtrechtUtrecht, Netherlands.
Marianne C VerhaarDepartment of Nephrology and Hypertension, University Medical Center UtrechtUtrecht, Netherlands.
University Medical Center Utrecht · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Since the mid-1980s magnetic resonance imaging (MRI) has been investigated as a non- or minimally invasive tool to probe kidney allograft function. Despite this long-standing interest, MRI still plays a subordinate role in daily practice of transplantation nephrology. With the introduction of new functional MRI techniques, administration of exogenous gadolinium-based contrast agents has often become unnecessary and true non-invasive assessment of allograft function has become possible. This raises the question why application of MRI in the follow-up of kidney transplantation remains restricted, despite promising results. Current literature on kidney allograft MRI is mainly focused on assessment of (sub) acute kidney injury after transplantation. The aim of this review is to survey whether MRI can provide valuable diagnostic information beyond 1 year after kidney transplantation from a mechanistic point of view. The driving force behind chronic allograft nephropathy is believed to be chronic hypoxia. Based on this, techniques that visualize kidney perfusion and oxygenation, scarring, and parenchymal inflammation deserve special interest. We propose that functional MRI mechanistically provides tools for diagnostic work-up in long-term follow-up of kidney allografts.

Indexed as

chronic allograft nephropathychronic hypoxia theoryfunctional MRIkidney transplantation follow-upmagnetic resonance imagingprotocol kidney biopsy

Identifiers

PMID28559850
PMCPMC5432553
OpenAlexW2614722521

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.