Evidence map›Paper›PMID 28559747›Full record

ArticleJournal of machine learning research : JMLR2016

Structure-Leveraged Methods in Breast Cancer Risk Prediction.

Jun Fan, Yirong Wu, Ming Yuan, David Page, Jie Liu, Irene M Ong, Peggy Peissig, Elizabeth Burnside

Abstract read
In one paragraph

Article in Journal of machine learning research : JMLR, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Prediction of Breast Cancer using Machine Learning Approaches.Journal of biomedical physics & engineering · 2022
    Article
  2. Review
  3. Article
  4. Article
  5. Quantifying predictive capability of electronic health records for the most harmful breast cancer.Proceedings of SPIE--the International Society for Optical Engineering · 2018
    Article
  6. Article
  7. Utility of Genetic Testing in Addition to Mammography for Determining Risk of Breast Cancer Depends on Patient Age.AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jun FanDepartment of Statistics, University of Wisconsin-Madison, 1300 University Avenue, Madison, WI 53706, United States, junfan@stat.wisc.edu.
Yirong WuDepartment of Radiology, University of Wisconsin-Madison, 600 Highland Avenue, Madison, WI 53792, United States, YWu@uwhealth.org.
Ming YuanDepartment of Statistics, University of Wisconsin-Madison, 1300 University Avenue, Madison, WI 53706, United States, myuan@stat.wisc.edu.
David PageDepartment of Biostatistics and Medical Informatics, University of Wisconsin-Madison, 600 Highland Avenue, Madison, WI 53792, United States, PAGE@biostat.wisc.edu.
Jie LiuDepartment of Genome Sciences, University of Washington-Seattle, 3720 15th Avenue, Seattle, WA 98105, United States, liu6@uw.edu.
Irene M OngDepartment of Biostatistics and Medical Informatics, University of Wisconsin-Madison, 600 Highland Avenue, Madison, WI 53792, United States, ONG@cs.wisc.edu.
Peggy PeissigMarshfield Clinic Research Foundation, 1000 North Oak Avenue, Marshfield, WI 54449, United States, peissig.peggy@mcrf.mfldclin.edu.
Elizabeth BurnsideDepartment of Radiology, University of Wisconsin-Madison, 600 Highland Avenue, Madison, WI 53792, United States, EBurnside@uwhealth.org.

Funding

UW COMPREHENSIVE CANCER CENTER SUPPORTP30CA014520 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI Christian Capitini · 1985 to 2026
$142.6M
Institutional Clinical and Translational Science AwardUL1TR000427 · NCATS · UNIVERSITY OF WISCONSIN-MADISON · PI DREZNER, MARC KENNETH · 2012 to 2016
$32.2M
TrainingU54AI117924 · NIAID · UNIVERSITY OF WISCONSIN-MADISON · PI CRAVEN, MARK W. · 2014 to 2018
$11.3M
Machine Learning for Identifying Adverse Drug EventsR01GM097618 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI CALDWELL, MICHAEL DEFOIX, HANSEN, RICHARD A. · 2011 to 2018
$3.8M
Secure Sharing of Clinical History & Genetic Data: Empowering Predictive Pers. MeR01LM011028 · NLM · UNIVERSITY OF WISCONSIN-MADISON · PI PAGE, CHARLES DAVID · 2011 to 2014
$2.2M
Breast Cancer GWAS: Function and Environmental InteractionsR01ES017400 · NIEHS · UNIVERSITY OF WISCONSIN-MADISON · PI GOULD, MICHAEL N, NEWTON, MICHAEL A · 2009 to 2013
$2.1M
Machine Learning for Improved Mammography ScreeningR01CA127379 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI BURNSIDE, ELIZABETH S · 2007 to 2010
$1.4M
Mentoring And Research In Patient-Oriented Breast Cancer DiagnosisK24CA194251 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI BURNSIDE, ELIZABETH S · 2015 to 2019
$963k
NCATS NIH HHS UL1 TR000427NCI NIH HHS K24 CA194251NCI NIH HHS P30 CA014520NCI NIH HHS R01 CA127379NIAID NIH HHS U54 AI117924NIEHS NIH HHS R01 ES017400NIGMS NIH HHS R01 GM097618NLM NIH HHS R01 LM011028
6 · The paper itself

Abstract

Predicting breast cancer risk has long been a goal of medical research in the pursuit of precision medicine. The goal of this study is to develop novel penalized methods to improve breast cancer risk prediction by leveraging structure information in electronic health records. We conducted a retrospective case-control study, garnering 49 mammography descriptors and 77 high-frequency/low-penetrance single-nucleotide polymorphisms (SNPs) from an existing personalized medicine data repository. Structured mammography reports and breast imaging features have long been part of a standard electronic health record (EHR), and genetic markers likely will be in the near future. Lasso and its variants are widely used approaches to integrated learning and feature selection, and our methodological contribution is to incorporate the dependence structure among the features into these approaches. More specifically, we propose a new methodology by combining group penalty and [Formula: see text] (1 ≤

Indexed as

breast cancer risk predictiongenetic variantsmammography descriptorspersonalized medicinestructure information

Identifiers

PMID28559747
PMCPMC5446896

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.