ArticleActa Cardiologica Sinica2017
Aortic Arch Calcification Associated with Cardiovascular Events and Death among Patients with Acute Coronary Syndrome.
Article in Acta Cardiologica Sinica, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.
- Thoracic Aorta Calcification and Risk of All-Cause Mortality and Cardiovascular Outcomes:Sultan Qaboos University medical journal · 2026Pooled it
- Incidental Finding of Coronary and Non-Coronary Artery Calcium: What Do Clinicians Need To Know?Current atherosclerosis reports · 2025Review
- Precranial artery calcification burden: a potential indicator of the clinical outcome of reperfusion in patients with acute large artery occlusion.The Journal of international medical research · 2024Observational
- Multimodal Cardiac Imaging in the Assessment of Patients Who Have Suffered a Cardioembolic Stroke: A Review.Journal of cardiovascular development and disease · 2023Review
- The Relationship Between Aortic Arch Calcification and Recurrent Stroke in Patients With Embolic Stroke of Undetermined Source-A Case-Control Study.Frontiers in neurology · 2022Article
- Arterial calcification at multiple sites: sex-specific cardiovascular risk profiles and mortality risk-the Rotterdam Study.BMC medicine · 2020Article
- Predictive value of abdominal aortic calcification index for mid-term cardiovascular events in patients with acute coronary syndrome.Heart and vessels · 2020Article
- Article
- 2019 Consensus Statement of the Taiwan Hypertension Society and the Taiwan Society of Cardiology on Renal Denervation for the Management of Arterial Hypertension.Acta Cardiologica Sinica · 2019Review
- Association between acute aortic dissection and the distribution of aortic calcification.PloS one · 2019Article
- The Relationship between Heart Rate Variability and Aortic Knob Width.Korean journal of family medicine · 2019Article
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Authors and funding
6 authors at 5 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTo date, it remains unsettled whether aortic arch calcification (AAC) has prognostic value in patients with acute coronary syndrome.
methodsFrom January 1 to December 31, 2013, a total of 225 patients with acute coronary syndrome (mean age 72 ± 26 years, 75% male) were enrolled in this study. Patients admitted to the coronary care unit of a tertiary referral medical center under the preliminary diagnosis of acute coronary syndrome were retrospectively investigated. The primary endpoint was composite of long-term major adverse cardiovascular events. The secondary endpoints were 30-day and long-term all-cause mortality.
resultsOf the 225 patients enrolled in this study, 143 had detectable AAC. Those who had AAC were older, with higher Killip classification and thrombolysis in myocardial infarction (TIMI) score with a lower probability of single vessel disease. Acute coronary syndrome patients with AAC had significantly higher 30-day mortality (17.3% vs. 7.1%, log-rank p = 0.02). During a mean follow-up period of 165 ± 140 days (maximum 492 days), the calcification group had significantly increased cardiovascular deaths (27.6% vs. 11.2%, log-rank p = 0.002), all-cause mortality (28.3% vs. 11.2%, log-rank p = 0.001) and composite endpoint of major adverse cardiovascular events (39.4% vs. 24.6%, log-rank p = 0.01). After adjusting for age, gender, diabetes mellitus and hypertension, AAC was an independent risk factor for primary and secondary endpoints among patients with acute coronary syndrome.
conclusionsAAC provided valuable prognostic information on clinical outcomes in patients with acute coronary syndrome. However, different treatment strategies would be warranted for optimal risk reduction in such a population.
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