ArticleActa Cardiologica Sinica2017
Clinical Characteristics of Patients Less than Forty Years Old with Coronary Artery Disease in Taiwan: A Cross-Sectional Study.
Article in Acta Cardiologica Sinica, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 28 citations in OpenAlex.
- Percutaneous coronary intervention in patients aged ≤40 years: a 10-year single-centre cohort study.Frontiers in cardiovascular medicine · 2026Article
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- Prevalence of antecedent Kawasaki disease in young adults with suspected acute coronary syndrome in high incidence cohort.Frontiers in cardiovascular medicine · 2023Article
- Lipid Profile and Small Dense Low-Density Lipoprotein in Acute Coronary Syndrome Patients: Relationships to Demographic, Clinical, Angiographic, and Therapeutic Variables.Journal of clinical medicine · 2022Article
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- Muscular Strength and Carotid Intima-Media Thickness in Physically Fit Young Adults: The CHIEF Atherosclerosis Study.Journal of clinical medicine · 2022Article
- Cardiorespiratory Fitness and Carotid Intima-Media Thickness in Physically Active Young Adults: CHIEF Atherosclerosis Study.Journal of clinical medicine · 2022Article
- Profiles of Hospitalized Patients with Angiographic Coronary Heart Disease in Taiwan during 2014-2016: Report of a Tertiary Hospital.Acta Cardiologica Sinica · 2021Article
- Simple model of atherosclerosis in cylindrical arteries: impact of anisotropic growth on Glagov remodeling.Mathematical medicine and biology : a journal of the IMA · 2021Article
- Pattern of coronary arterial lesions amongst Saudi Arabians: a cross-sectional coronary fluoroscopic angiography study.The Pan African medical journal · 2020Article
- Clinical, Demographic, and Biochemical Characteristics of Patients with Acute ST-Segment Elevation Myocardial Infarction: An Analysis of Acute Coronary Syndrome Registry Data of a Single Medical Center from 2005 to 2016.Acta Cardiologica Sinica · 2020Article
- The Correlation between Waist-Hip Ratio and Achieving Therapeutic Lipid Goals in Taiwan.Acta Cardiologica Sinica · 2019Article
- Correlation between Gout and Coronary Heart Disease in Taiwan: A Nationwide Population-Based Cohort Study.Acta Cardiologica Sinica · 2019Article
- The Utilization of Stress Tests Prior to Percutaneous Coronary Intervention for Stable Coronary Artery Disease in Taiwan.Acta Cardiologica Sinica · 2019Article
- Associations of Ambient Temperature with Mortality Rates of Cardiovascular and Respiratory Diseases in Taiwan: A Subtropical Country.Acta Cardiologica Sinica · 2018Article
- Epidemiological and clinical profile, management and outcomes of young patients (≤40 years) with acute coronary syndrome: A single tertiary care center study.Indian heart journalArticle
- Can QRISK-3 and PREVENT Predict Premature Acute Coronary Syndrome in Adults under 40 Years? The Insights from Predicting the Risk of Acute Coronary Syndrome under 40 (PRACS-40) Study.Heart views : the official journal of the Gulf Heart AssociationArticle
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCoronary artery disease (CAD) rarely occurs in young adults. Our objective was to investigate the baseline characteristics and outcomes of young patients with CAD.
methodsWe retrospectively enrolled patients aged < 40 years of age who underwent coronary angiography in a tertiary hospital in Taiwan between 2002 and 2015. The baseline characteristics and in-hospital outcomes of patients with acute coronary syndrome (ACS) and occlusive CAD (stenotic lesions > 50%) were compared with those of patients without ACS and non-occlusive CAD, respectively.
resultsWe enrolled 245 young patients including 131 (53.5%) with ACS and 178 with occlusive CAD. The median age of the patients was 36.08 years and the mean follow-up period was 4.84 years. Of all study subjects, 220 (89.8%) were men and 140 (57.1%) were current smokers; there was an overall in-hospital mortality rate of 3.3%. Furthermore, age, body mass index, smoking, total leukocyte count, neutrophil-to-lymphocyte ratio, total cholesterol, and low-density lipoprotein were higher in patients with ACS and significant CAD than in those without ACS and nonstenotic CAD. Interestingly, triglyceride (TG) levels and the TG to high-density lipoprotein ratio were significantly higher in patients with ACS and occlusive CAD than in those without ACS and non-occlusive CAD. Logistic regression analysis revealed that smoking is an independent predictor of ACS and occlusive CAD.
conclusionsOur findings suggest that classical risk factors, obesity, and inflammation remain potent contributors to occlusive CAD and ACS in young adults in Taiwan. Efforts to prevent or minimize these risk factors, such as smoking cessation and aggressive lipid control, are necessary in young adults.
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