Evidence map›Paper›PMID 28559611›Full record

ArticleJournal of food science and technology2017

A benign alternative process for efficient separation of pure commercially important flavonoid nutraceuticals from edible plants.

Shankar Subramaniam, Ravikumar Raju, Aravind Sivasubramanian

Abstract read
In one paragraph

Article in Journal of food science and technology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

3 authors.

Shankar SubramaniamSchool of Chemical and Biotechnology, SASTRA University, Thanjavur, 613402 India.
Ravikumar RajuDepartment of Chemistry, Vivekanandha College of Arts and Sciences for Women (Autonomous), Elayampalayam, 637 205 India.
Aravind SivasubramanianSchool of Chemical and Biotechnology, SASTRA University, Thanjavur, 613402 India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present study signifies the development of a unique, optimized procedure for both selective determination and separation of different flavonoid nutraceuticals from edible plants. Totally ten different flavonoids were determined (HPLC-DAD) and isolated from five different plants using the developed process with a remarkable purity of 91-98% and recovery of 88-95%. Box-Behnken experimental design model yielded a optimized amount of 40.36 mg/g of AI extract (Pinostrobin) and 28.95 mg/g of AI extract (Baicalein) with a high correlation coefficient (0.98-0.99), indicating a good fit between the second order regression model and the experimental observations. The final purity of compounds through optimized process is 97.1% (Pinostrobin) and 93.5% (Baicalein) respectively. The optimized yields depicted a total recovery of 92% for pinostrobin, and 89% for Baicalein respectively. Thus, the developed process worked as a potential alternative which when statistically optimized results in a remarkable recovery of flavonoids from various plants. Being an environmentally friendly protocol the process could be useful in industrial separation of commercially important flavonoids widely applied in food industry.

Indexed as

Alternative processBox–BehnkenFlavonoidsNutraceuticalspH gradientPhyto-molecule separation

Identifiers

PMID28559611
PMCPMC5430184

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.