Evidence map›Paper›PMID 28559482›Full record

ArticlemBio2017

A Screen for

Kuang Hu, Irina Artsimovitch

Open access · goldAbstract read
In one paragraph

Article in mBio, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. mBio · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Kuang HuDepartment of Microbiology and The Center for RNA Biology, The Ohio State University, Columbus, Ohio, USA.
Irina ArtsimovitchDepartment of Microbiology and The Center for RNA Biology, The Ohio State University, Columbus, Ohio, USA artsimovitch.1@osu.edu.
The Ohio State University · US

Funding

Mechnanism of transcript elongation control by RfaHR01GM067153 · NIGMS · OHIO STATE UNIVERSITY · PI IRINA ARTSIMOVITCH · 2003 to 2026
$8.0M
NIGMS NIH HHS R01 GM067153
6 · The paper itself

Abstract

RfaH activates horizontally acquired operons that encode lipopolysaccharide core components, pili, toxins, and capsules. Unlike its paralog NusG, which potentiates Rho-mediated silencing, RfaH strongly inhibits Rho. RfaH is recruited to its target operons via a network of contacts with an elongating RNA polymerase (RNAP) and a specific DNA element called

Indexed as

Bridged Bicyclo Compounds, HeterocyclicDNA-Directed RNA PolymerasesDNA ReplicationEscherichia coliEscherichia coli ProteinsModels, MolecularOperonPeptide Elongation FactorsRho FactorSodium Dodecyl SulfateSuppression, GeneticTrans-ActivatorsTranscription, GeneticTranscription Termination, GeneticbicozamycinBridged Bicyclo Compounds, HeterocyclicDNA-Directed RNA PolymerasesEscherichia coli ProteinsPeptide Elongation FactorsRfaH protein, E coliRho FactorSodium Dodecyl SulfateTrans-ActivatorspolarityRfaHRhoRNA polymerasetermination

Identifiers

PMID28559482
PMCPMC5449661
OpenAlexW2617922647

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.